Success Metrics

Clinical Success Rate
70.1%

Based on 47 completed trials

Completion Rate
70%(47/67)
Active Trials
40(31%)
Results Posted
64%(30 trials)
Terminated
20(15%)

Phase Distribution

Ph phase_3
22
17%
Ph early_phase_1
4
3%
Ph not_applicable
29
22%
Ph phase_1
33
25%
Ph phase_2
37
28%

Phase Distribution

37

Early Stage

37

Mid Stage

22

Late Stage

Phase Distribution125 total trials
Early Phase 1First-in-human
4(3.2%)
Phase 1Safety & dosage
33(26.4%)
Phase 2Efficacy & side effects
37(29.6%)
Phase 3Large-scale testing
22(17.6%)
N/ANon-phased studies
29(23.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

59.5%

47 of 79 finished

Non-Completion Rate

40.5%

32 ended early

Currently Active

40

trials recruiting

Total Trials

131

all time

Status Distribution
Active(42)
Completed(47)
Terminated(32)
Other(10)

Detailed Status

Completed47
Terminated20
Active, not recruiting20
Recruiting20
Withdrawn12
unknown9

Development Timeline

Analytics

Development Status

Total Trials
131
Active
40
Success Rate
70.1%
Most Advanced
Phase 3

Trials by Phase

Early Phase 14 (3.2%)
Phase 133 (26.4%)
Phase 237 (29.6%)
Phase 322 (17.6%)
N/A29 (23.2%)

Trials by Status

terminated2015%
active_not_recruiting2015%
unknown97%
completed4736%
withdrawn129%
suspended11%
not_yet_recruiting22%
recruiting2015%

Recent Activity

Clinical Trials (131)

Showing 20 of 131 trialsScroll for more
NCT00950001Phase 3

Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases

Active Not Recruiting
NCT03741673Phase 3

Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases

Active Not Recruiting
NCT03604978Phase 1

Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma

Active Not Recruiting
NCT02306161Phase 3

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Active Not Recruiting
NCT02886585Phase 2

Pembrolizumab In Central Nervous System Metastases

Active Not Recruiting
NCT06287515Phase 1

Hypophysectomy by Stereotactic Radiosurgery for Cancer-Related Pain

Recruiting
NCT04711824Phase 1

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

Active Not Recruiting
NCT02390518Phase 1

Stereotactic Radiosurgery Dose Escalation for Brain Metastases

Recruiting
NCT04804644Phase 3

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Recruiting
NCT06500455Phase 3

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Recruiting
NCT05789589Phase 1

Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases

Suspended
NCT03750227Phase 3

Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

Recruiting
NCT05419076Phase 2

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

Recruiting
NCT03508752Phase 1

Neurocognitive Decline in Patients With Brain Metastases

Active Not Recruiting
NCT05023772Not Applicable

Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

Recruiting
NCT07578116Phase 3

Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis

Not Yet Recruiting
NCT03184038Not Applicable

Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

Recruiting
NCT02696993Phase 1

Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer

Active Not Recruiting
NCT04588246Phase 3

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Terminated
NCT05438212Phase 3

Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

Active Not Recruiting

Drug Details

Intervention Type
RADIATION
Total Trials
131