Success Metrics

Clinical Success Rate
69.7%

Based on 46 completed trials

Completion Rate
70%(46/66)
Active Trials
42(32%)
Results Posted
63%(29 trials)
Terminated
20(15%)

Phase Distribution

Ph early_phase_1
4
3%
Ph phase_2
37
28%
Ph phase_3
21
16%
Ph phase_1
33
25%
Ph not_applicable
29
22%

Phase Distribution

37

Early Stage

37

Mid Stage

21

Late Stage

Phase Distribution124 total trials
Early Phase 1First-in-human
4(3.2%)
Phase 1Safety & dosage
33(26.6%)
Phase 2Efficacy & side effects
37(29.8%)
Phase 3Large-scale testing
21(16.9%)
N/ANon-phased studies
29(23.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

59.0%

46 of 78 finished

Non-Completion Rate

41.0%

32 ended early

Currently Active

42

trials recruiting

Total Trials

130

all time

Status Distribution
Active(43)
Completed(46)
Terminated(32)
Other(9)

Detailed Status

Completed46
Recruiting23
Terminated20
Active, not recruiting19
Withdrawn12
unknown9

Development Timeline

Analytics

Development Status

Total Trials
130
Active
42
Success Rate
69.7%
Most Advanced
Phase 3

Trials by Phase

Early Phase 14 (3.2%)
Phase 133 (26.6%)
Phase 237 (29.8%)
Phase 321 (16.9%)
N/A29 (23.4%)

Trials by Status

terminated2015%
withdrawn129%
active_not_recruiting1915%
completed4635%
recruiting2318%
not_yet_recruiting11%
unknown97%

Recent Activity

Clinical Trials (130)

Showing 20 of 130 trialsScroll for more
NCT05438212Phase 3

Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

Active Not Recruiting
NCT04804644Phase 3

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Recruiting
NCT06466720

Measuring and Mapping Cognitive Decline After Brain Radiosurgery

Active Not Recruiting
NCT06500455Phase 3

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Recruiting
NCT05522660Phase 3

Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer

Recruiting
NCT00872625Phase 1

Radiation Therapy and Docetaxel Followed by Standard Therapy in Treating Women With Breast Cancer

Completed
NCT05341349Phase 1

Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases

Terminated
NCT01899261Not Applicable

Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Completed
NCT02713269Phase 2

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

Active Not Recruiting
NCT07535463Phase 1

A Study of Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People With Non-Small Cell Lung Cancer

Recruiting
NCT06204315Phase 2

Risk Adapted Spinal Cord/Cauda Constraint Relaxation for High-risk Patients With Metastatic Epidural Spinal Cord Compression Undergoing Spine Stereotactic Radiosurgery

Recruiting
NCT02645487Not Applicable

Stereotactic Radiosurgery (SRS) Dose-Escalation Study for Brain Metastasis

Active Not Recruiting
NCT06649058Phase 2

EXCLAIM: Exploring Combined Local and Systemic Approaches In Brain Metastasis: a Multi-cohort Randomized Phase II Study Evaluating Initial Response to Systemic Therapy and Subsequent Integration of Stereotactic Radiosurgery in Patients With Low-risk Brain Metastases and Central Nervous System-active

Recruiting
NCT04659811Phase 2

Stereotactic Radiosurgery and Immunotherapy (Pembrolizumab) for the Treatment of Recurrent Meningioma

Active Not Recruiting
NCT02387905Phase 2

Cement Augmentation in Preventing Vertebral Body Compression Fracture Following Spine Stereotactic Radiosurgery in Patients With Solid Tumors and Spinal Metastases

Active Not Recruiting
NCT05222620Phase 2

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

Recruiting
NCT02306161Phase 3

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Active Not Recruiting
NCT03604978Phase 1

Nivolumab and Multi-fraction Stereotactic Radiosurgery With or Without Ipilimumab in Treating Patients With Recurrent Grade II-III Meningioma

Active Not Recruiting
NCT05178472Not Applicable

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

Recruiting
NCT05987644Phase 1

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements

Recruiting

Drug Details

Intervention Type
RADIATION
Total Trials
130