NCT05270616

Brief Summary

To compare the safety/efficacy of the robotic-assisted lobectomy/segmentectomy (RAL/S) with the video-assisted lobectomy/segmentectomy (VAL/S) for lung resection. Video-assisted lobectomy/segmentectomy (VAL/S) for lung resection is divided into uniport group and multiple- port group.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
800

participants targeted

Target at P75+ for not_applicable

Timeline
25mo left

Started Jun 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress74%
Jun 2020Jun 2028

Study Start

First participant enrolled

June 1, 2020

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

February 27, 2022

Completed
9 days until next milestone

First Posted

Study publicly available on registry

March 8, 2022

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2023

Completed
5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2028

Expected
Last Updated

March 8, 2022

Status Verified

February 1, 2022

Enrollment Period

3 years

First QC Date

February 27, 2022

Last Update Submit

February 27, 2022

Conditions

Keywords

robotic surgeryVATSuniportmultiport

Outcome Measures

Primary Outcomes (10)

  • mortality

    incidence rate

    30 days after surgery

  • conversion rate to open surgery

    incidence rate

    during surgery

  • postoperative complications

    incidence rate

    within 7 days after surgery

  • operation time

    minutes

    within 180 minutes

  • duration of hospitalization

    days

    within 7 days after surgery

  • days to tube removal

    days

    within 7 days after surgery

  • retrieved lymph node

    amount

    within 1 days after surgery

  • retrieved lymph node station

    amount

    within 1 days after surgery

  • short- term PFS

    proportion

    3 years

  • short- term overall survival

    proportion

    3 years

Study Arms (3)

robotic surgery group

EXPERIMENTAL

minimally invasive lung surgery using the Davinci robotic system to assist.

Procedure: robotic surgery

uniport surgery group

ACTIVE COMPARATOR

VATS minimally invasive lung surgery under the uniportal status.

Procedure: uniport surgery

multiple- port surgery group

ACTIVE COMPARATOR

VATS minimally invasive lung surgery under the multiple- port status.

Procedure: multiple- port surgery

Interventions

minimally invasive surgery using the Davinci robotic system

robotic surgery group

VATS minimally invasive surgery under the uniportal status

uniport surgery group

VATS minimally invasive surgery under the multiple- port status

multiple- port surgery group

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • good cardio- pulmonary function to tolerate surgery;
  • minimaly invasive surgery for lobectomy or segmentectomy or sleeve lobectomy;

You may not qualify if:

  • cardio- pulmonary function is not good enough to tolerate surgery;
  • huge tumor or extensive adhesion in thoracic cavity.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Second Hospital of Shandong University

Jinan, Shandong, 250033, China

RECRUITING

MeSH Terms

Conditions

Lung Diseases

Interventions

Robotic Surgical Procedures

Condition Hierarchy (Ancestors)

Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Surgery, Computer-AssistedSurgical Procedures, OperativeRoboticsAutomationTechnologyTechnology, Industry, and Agriculture

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 27, 2022

First Posted

March 8, 2022

Study Start

June 1, 2020

Primary Completion

June 1, 2023

Study Completion (Estimated)

June 1, 2028

Last Updated

March 8, 2022

Record last verified: 2022-02

Locations