The Diagnostic Role of Adding the Hoffman Reflex Study for L5 Radiculopathy in the Electrodiagnostic Laboratory

NCT05269602 | Completed

• 1 other identifier: HKara1
• Study Type: observational
• Target: 58
• Locations: 1 country
• Sites: 2

Brief Summary

The H-reflex is one of the most popular topics in reflexology and one of the late responses involved in routine nerve conduction studies in the electromyography (EMG) laboratory. The H-reflex is generally recorded from the gastrocnemius-soleus muscles (tibial H-reflex) by stimulating the tibial nerve in the lower extremity. Tibial H-reflex is a sensitive measurement for examining S1 radiculopathy. Although there are plenty of studies related to the Soleus muscle registered H-reflex in S1 radiculopathy in the literature, there is no study in which the H-reflex is used in L5 muscles in diagnosing L5 radiculopathies. The aim of this study is to investigate the effectiveness of the H-reflex by using a different method in the distinction between L5 and S1 radiculopathies.

Conditions

Radiculopathy; Hoffman's Reflex

Keywords

Electrodiagnosis

Outcome Measures

Primary Outcomes (1)

• The Hoffman reflex latency

  The Hoffman reflex latency evaluated after electromyography

  1 day

Study Arms (2)

L5 Radiculopathy

Patients who have Lumbar 5 root compression with the Magnetic Resonance İmaging

S1 Radiculopathy

Patients who have Sacral 1 root compression with the Magnetic Resonance İmaging

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A total of 58 patients admitted applied to the outpatient clinics due to unilateral radicular back pain and who had L5 or S1 root compression in magnetic resonance imaging (MRI) participated in this study.

You may qualify if:

• Between 18 and 65 years of age
• Low back pain for at least three months
• Radicular pain in one extremity, disc herniation that matches painful dermatome and root compression in MRI(L5 or S1 root compression)
• MRI and physical examination findings compatible with root compression
• No contraindications to EMG.

You may not qualify if:

• Bilateral radicular symptoms
• Multiple levels of radiculopathy
• Diabetes
• Polyneuropathy
• Rheumatic diseases
• History of malignancies
• Lumbosacral region spine surgery
• Lumbar spinal stenosis
• Spondylolisthesis
• Previous peripheral neuropathy in the lower extremities
• Different causes of radiculopathy other than disc herniation (e.g. tumor, osteophyte, facet hypertrophy and other)
• Central system disorders
• Muscular diseases

Sponsors & Collaborators

• TC Erciyes University: lead

Study Sites (2)

Gazi University Faculty of Medicine

Ankara, Besevler, 06500, Turkey (Türkiye)

Location

Selcuk University Faculty of Medicine

Konya, Selcuklu, 42130, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Radiculopathy; Reflex, Abnormal

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor, physiatrist

Study Record Dates

• First Submitted: February 15, 2022
• First Posted: March 8, 2022
• Study Start: December 1, 2017
• Primary Completion: December 1, 2018
• Study Completion: December 1, 2019
• Last Updated: March 22, 2022

Record last verified: 2022-03

Locations

TU (2)