Adductor Canal Block Combined With IPACK vs Genicular Nerves Block in Knee Arthroscopy

NCT05269095 | Unknown

• 1 other identifier: 35236/1/22
• Study Type: interventional
• Target: 105
• Locations: 0 countries
• Sites: N/A

Brief Summary

This prospective randomized controlled study is designed to investigate the postoperative analgesic effect of adductor canal block (ACB) combined with infiltration of the interspace between the popliteal artery and the capsule of posterior knee (IPACK) block compared to genicular nerves block in patients undergoing knee arthroscopy.

Conditions

Arthroscopy; Genicular Nerves Block

Outcome Measures

Primary Outcomes (1)

• Postoperative 24-hour rescue analgesic consumption

  Total postoperative 24-hour rescue analgesic consumption will be recorded

  24 hours postoperative

Secondary Outcomes (2)

• Post-operative pain

  24 hours Postoperative

• Time taken till 1st rescue analgesic request

  24 hours Postoperative

Study Arms (3)

spinal anesthesia only

EXPERIMENTAL

Patients will receive spinal anesthesia only

Procedure: Spinal anesthesia only

spinal anesthesia and ultrasound-guided Genicular nerves block

EXPERIMENTAL

Patients will receive spinal anesthesia and ultrasound-guided Genicular nerves block

Biological: Spinal anesthesia and ultrasound-guided Genicular nerves block

Spinal anesthesia and US guided Adductor canal nerve block plus infiltration of the interspace

EXPERIMENTAL

Patients will receive spinal anesthesia and ultrasound-guided Adductor canal nerve block plus infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (PACK) block.

Biological: Ultrasound-guided Adductor Canal block (ACB) technique with infiltration of the interspace between popliteal artery and the capsule of posterior knee block ('PACK)

Interventions

Spinal anesthesia only PROCEDURE

Patients will receive spinal anesthesia with 2-3 ml 0.5% (10-15 mg) hyperbaric bupivacaine plus 25 ug fentanyl at the L3/4 interspaces.

spinal anesthesia only

Spinal anesthesia and ultrasound-guided Genicular nerves block BIOLOGICAL

Patients will receive16 ml bupivacaine 0025% will be administered, and4 ml of this solution will be placed at each of the 4 target nerves.

spinal anesthesia and ultrasound-guided Genicular nerves block

Ultrasound-guided Adductor Canal block (ACB) technique with infiltration of the interspace between popliteal artery and the capsule of posterior knee block ('PACK) BIOLOGICAL

Adductor Canal block (ACB) technique will be performed using 16 ml bupivacaine 0025% As regarding the Popliteal artery and the capsule of posterior knee block ('PACK), it will be performed Using 16 ml bupivacaine 0.25%

Spinal anesthesia and US guided Adductor canal nerve block plus infiltration of the interspace

Eligibility Criteria

• Age: 21 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age 21-60 years
• Both genders
• American Society of Anaesthesiologists physical status classification I - III
• Patients scheduled for elective unilateral knee arthroscopy under spinal anesthesia

You may not qualify if:

• Patient refusal
• Preoperative neurological deficits
• Opioid-dependent (opioid intake more than 3 months)
• Chronic pain conditions
• Significant cardiac and respiratory disease
• Pre-existing major organ dysfunction such as hepatic and renal failure
• Coexisting hematological disorder or deranged coagulation parameters
• Psychiatric illnesses
• Allergy to any of the drugs used in the study

Sponsors & Collaborators

• Tanta University: lead

MeSH Terms

Interventions

Anesthesia, Spinal; Methods

Intervention Hierarchy (Ancestors)

Anesthesia, Conduction; Anesthesia; Anesthesia and Analgesia; Investigative Techniques

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of Anesthesiology and Surgical Intensive Care and Pain Medicine

Study Record Dates

• First Submitted: March 4, 2022
• First Posted: March 7, 2022
• Study Start: March 21, 2022
• Primary Completion: March 20, 2023
• Study Completion: March 21, 2023
• Last Updated: March 24, 2022

Record last verified: 2022-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: One year after the end of the study