Revascularisation of Autotransplanted Teeth
1 other identifier
observational
16
1 country
1
Brief Summary
Retrospective Analysis of a Study cohort that experienced autotransplantation of mature teeth with simultaneous root end resection Note: The study was registered on Clinicaltrials.gov after termination of study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Aug 2021
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 6, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
February 15, 2022
CompletedFirst Submitted
Initial submission to the registry
February 23, 2022
CompletedFirst Posted
Study publicly available on registry
March 4, 2022
CompletedMarch 20, 2026
March 1, 2026
6 months
February 23, 2022
March 17, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Survival
Tooth survival
1 year
Secondary Outcomes (1)
Revascularisation
1 year
Study Arms (1)
Autotransplantation
Autotransplantation and apicoectomy of mature teeth
Interventions
Eligibility Criteria
Patients who underwent Autotransplantation of mature teeth with simultaneous apicoectomy between July 2017 and July 2020
You may qualify if:
- Male and female consenting and judicious young people and adults
- Written consent of the participant and, if applicable, of the legal guardian after education
- Planned tooth transplantation with advanced or completed root growth
You may not qualify if:
- Contraindications for magnetic resonance imaging (MRI): (pronounced metal restorations, running orthodontics with metal, fixed appliance in the target jaw)
- Current or past antiresorptive therapy with bisphosphonates
- Further anamnestic general or local risk situation, among others: Anti-angiogenic therapy, History of local radiation therapy, severe coagulation disorder, unadjusted diabetes mellitus, malignant diseases
- Acute gingivitis or advanced periodontitis
- Participation in an ongoing drug trial (various drugs may distort the result, such as bisphosphonates, cortisone, chemotherapeutics, angiogenesis inhibitors)
- heavy smokers (\> 10 per day)
- Acute or chronic infections (osteomyelitis) at the surgical site
- metabolic diseases (diabetes, hyperparathyroidism, osteomalacia)
- Severe kidney dysfunction, severe liver disease
- Patients with high-dose corticosteroid therapy
- prolonged corticosteroid or radiotherapy in the oral cavity
- autoimmune diseases
- Pregnant or breastfeeding women
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Medical University of Graz
Graz, Styria, 8010, Austria
Related Publications (1)
Jakse N, Ruckenstuhl M, Rugani P, Kirnbauer B, Sokolowski A, Ebeleseder K. Influence of Extraoral Apicoectomy on Revascularization of an Autotransplanted Tooth: A Case Report. J Endod. 2018 Aug;44(8):1298-1302. doi: 10.1016/j.joen.2018.04.016. Epub 2018 Jun 20.
PMID: 29935869BACKGROUND
Biospecimen
Histological evaluation of lost teeth
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Petra Rugani, DDS
Medical University of Graz
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 23, 2022
First Posted
March 4, 2022
Study Start
August 6, 2021
Primary Completion
February 1, 2022
Study Completion
February 15, 2022
Last Updated
March 20, 2026
Record last verified: 2026-03