Barts Revascularisation Registry

NCT05255705 | Recruiting

• 1 other identifier: EDGE ID: 142567
• Study Type: observational
• Target: 20,000
• Locations: 1 country
• Sites: 1

Brief Summary

Despite the year-on-year decrease, coronary artery disease (CAD) still remains one of the leading cause of mortality worldwide. With advances in technology and our understanding of cardiac disease, we can now treat CAD using minimally invasive interventional techniques. This has revolutionised treatment for and improved the lives of many patients with CAD. Although trials have assessed various therapeutic strategies in various populations, real-world evidence of intervention and medical treatment among patients with CAD is increasingly recognised as an important part of providing safety and efficacy data and improving the care we provide. This data will add to that literature by assessing the characteristics and outcomes of patients with CAD. It will also identify and characterise predictors of outcomes, improve risk stratification and diagnostic evaluation.

Conditions

Myocardial Infarction; Stable Angina

Outcome Measures

Primary Outcomes (3)

• Mortality

  Assessment of Mortality

  1 year

• Re-admission rates post Revascularisation

  Re-admission

  1 year

• MACE post Revascularisation

  MACE

  1 year

Study Arms (1)

Patients undergoing Revascularisation at Barts Heart Centre

This study aims to assess, in a real-world setting, the safety, efficacy and feasibility of further investigations in patients with coronary artery disease undergoing revascularisation.

Other: Observation only

Interventions

Observation only OTHER

Observation only

Patients undergoing Revascularisation at Barts Heart Centre

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study will include all patients admitted to or reviewed at Barts Heart Centre (St. Bartholomew's Hospital) who undergo revascularisation. These patients range from young adults to the elderly and will include any patient ≥16 years of age. Patients who are followed up with and without any intervention (i.e. both medically managed patients as well as patients undergoing intervention) are equally as important and therefore we shall include both groups of patients. Patients will be included from referrals made by other clinicians either as in or outpatients. All these patients have their clinical data captured on a database or hospital based clinical programme.

You may qualify if:

• Informed consent will not be sought for, as patients are automatically included onto a database that we will use for research purposes.
• No children will be included in this study.
• Vulnerable adults or those unable to give consent will be included in the study as well if they are referred to the Interventional Cardiology team.
• Both male and female patients ≥16 years of age will be included
• All patients will have had an angiogram at BHC.
• Any patient who has undergone revascularisation.

You may not qualify if:

• Patients \<16 years will not be included in this study.

Sponsors & Collaborators

• Queen Mary University of London: lead

Study Sites (1)

Barts Health NHS Trust

London, United Kingdom

RECRUITING

MeSH Terms

Conditions

Myocardial Infarction; Angina, Stable

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis; Angina Pectoris; Chest Pain; Pain; Neurologic Manifestations; Signs and Symptoms

Central Study Contacts

Dr. Krishnaraj Rathod

CONTACT

02073773000; krishnaraj.rathod1@nhs.net

Dr. Daniel Jones

CONTACT

02073777000; dan.jones8@nhs.net

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 18, 2022
• First Posted: February 24, 2022
• Study Start: August 6, 2021
• Primary Completion: March 1, 2026
• Study Completion: March 1, 2026
• Last Updated: July 24, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)