Clinical and Radiographic of the Effect of Socket Preservation Using the Roll Pedicle Connective Tissue Graft With Bovine Bone: A Case Series Trial.

NCT05255341 | Completed

• 1 other identifier: roll pedicle graft
• Study Type: interventional
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

After tooth extraction, the residual alveolar ridge generally provides limited bone volume because of ongoing, progressive bone resorption. Healing events within post-extraction sockets reduce the dimensions of the socket over time. Therefore, socket preservation became an indispensable procedure as well as fundamental to prevent bone loss following tooth extraction. Preservation, by the name, is the maintenance of the socket, which is essentially the height and width of the gap that is left after the tooth is removed. It is done by placing a graft material or scaffold immediately into the socket of an extracted tooth to presto preserve bone height, width and density

Conditions

Socket Preservation

Keywords

socket preservation; vascularized interpositional connective tissue graft; alveolar ridge preservation techniques; bovine bone graft; roll pedicle graft

Outcome Measures

Primary Outcomes (1)

• width of alveolar bone

  Two holes will be made in the acrylic stent (3mm and 5 mm below the alveolar crest) on the buccal and palatal extensions within the midline of the tooth to be extracted. The buccopalatal width of the alveolar ridge will be measured at the two assigned points using bone caliper at baseline and 6 months post extraction

  changes in the Width of alveolar bone were measured at 3& 5 mm at baseline,3 months and 6 months

Secondary Outcomes (2)

• gingival thickness

  changes in the gingival thickness were measured at 3 & 5mm at (baseline,3 months and 6 months)

• height of the alveolar crest

  changes in height of alveolar crest were measured at baseline, 3 months and 6 months

Study Arms (1)

roll pedicle connective tissue graft with bovine bone

EXPERIMENTAL

1. sulcular incisions were performed on the buccal and lingual aspects of the teeth to be extracted 2. Atraumatic extraction was made by periotome. 3. After tooth extraction the soft tissue was reflected at least 4 mm beyond the alveolar crest margin and the socket was filled with bovine derived xenograft and covered with roll pedicle connective tissue graft as a barrier membrane. 4. This pedicle is rolled under the buccal mucosa.The palatal connective tissue pedicle graft was outlined by full thickness incision along the oblique incision line, and parallel incision given from the mesial line angle of target place and reflected coronally up to the crest of the ridge defect. then a partial thickness incision was made extending beyond the line angles of adjacent incisors and mucogingival junction, leaving the periosteum on the bone. 5. the pedicle graft was rolled from the apical end and secured with interrupted sutures to the labial flap.

Procedure: roll pedicle connective tissue graft with bovine bone

Interventions

roll pedicle connective tissue graft with bovine bone PROCEDURE

rotated pedicle connective tissue graft together with bovine bone applied for socket preservation after tooth extraction

Also known as: vascularized interpositional connective tissue graft

roll pedicle connective tissue graft with bovine bone

Eligibility Criteria

• Age: 27 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• patients with healthy systemic condition.
• Adult patients ˃ 18 years old.
• hopeless teeth that need tooth or root extraction in the maxillary esthetic zone.
• Alveolar socket Grade I and II.
• Normal platelet counts according to complete blood count (CBC) test done in the screening stage.

You may not qualify if:

• Acute infection at the extraction site
• Smokers ˃ 10 cigarettes / day.
• Medications that may interfere with wound healing
• History of treatment with bisphosphonates.
• History of allergic reaction

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Dentistry -Cairo University

Giza, 0020, Egypt

Location

Study Officials

• noha magdy salem amin

  cairo university- faculty of dentistry

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: February 8, 2022
• First Posted: February 24, 2022
• Study Start: July 16, 2019
• Primary Completion: March 1, 2021
• Study Completion: September 16, 2021
• Last Updated: March 11, 2022

Record last verified: 2022-02

Locations

EG (1)