NCT05247632

Brief Summary

The associations between food nutrition and safety factors with the risk of chronic diseases are still unclear. This study is conducted in Jinhua, a city with a high prevalence of chronic diseases in China, to assess relations between food nutrition and safety factors and chronic diseases.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,290

participants targeted

Target at P75+ for all trials

Timeline
26mo left

Started May 2018

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress79%
May 2018Jul 2028

Study Start

First participant enrolled

May 1, 2018

Completed
3.8 years until next milestone

First Submitted

Initial submission to the registry

February 3, 2022

Completed
18 days until next milestone

First Posted

Study publicly available on registry

February 21, 2022

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2024

Completed
4.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2028

Expected
Last Updated

January 10, 2024

Status Verified

March 1, 2023

Enrollment Period

6 years

First QC Date

February 3, 2022

Last Update Submit

January 7, 2024

Conditions

Chronic Diseases

Keywords

Food safetyFood nutritionFood contaminantMult-omicsChronic diseases

Outcome Measures

Primary Outcomes (3)

  • Numbers of participants with metabolic syndrome

    metabolic syndrome

    From entry into the study baseline:2018 until 2023

  • Numbers of participants with obesity

    Obesity

    From entry into the study baseline:2018 until 2023

  • Numbers of participants with diabetes

    Diabetes

    From entry into the study baseline:2018 until 2023

Secondary Outcomes (2)

  • Numbers of participants died

    From entry into the study baseline:2018 until 2023

  • Numbers of participants with cardiovascular diseases

    From entry into the study baseline:2018 until 2023

Other Outcomes (1)

  • Numbers of participants with fatty liver disease

    From entry into the study baseline:2018 until 2023

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Subjects are eligible residents from 10 government-administered units including 7 urban towns and 3 rural villages of Jinhua, China.

You may qualify if:

  • Subject aged ≥45 and ≤74 years old
  • Subject has complete data on diet and follow-up time

You may not qualify if:

  • had the major illness that had made personal life disabled

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Lanxi Red Cross Hospital

Lanxi, Zhejiang, 321100, China

Location

Lanxi Hospital of Traditional Chinese Medicine

Jinhua, China

Location

Biospecimen

Retention: SAMPLES WITH DNA

The investigators collected blood samples.

MeSH Terms

Conditions

Chronic Disease

Condition Hierarchy (Ancestors)

Disease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Weifang Zheng

    Lanxi Red Cross Hospital

    STUDY DIRECTOR

  • Jingjing Jiao

    Zhejiang University

    PRINCIPAL INVESTIGATOR

  • Yu Zhang

    Zhejiang University

    PRINCIPAL INVESTIGATOR

  • Pan Zhuang

    Zhejiang University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 3, 2022

First Posted

February 21, 2022

Study Start

May 1, 2018

Primary Completion

May 1, 2024

Study Completion (Estimated)

July 1, 2028

Last Updated

January 10, 2024

Record last verified: 2023-03

Locations

CN(2)