NCT05229367

Brief Summary

Mode specificity of eccentric and concentric isokinetic training have been examined in previous studies but with conflicting results. The present study aimed to examine the mode-specific effects of eccentric and concentric isokinetic training of hamstring muscle at slow angular velocity on eccentric peak torque of hamstring (PTecc), concentric peak torque of quadriceps (PTcon), acceleration time of hamstring (AThams) and quadriceps (ATquad), deceleration time of hamstring (DThams) and quadriceps (DTquad), time to peak torque of hamstring (TPThams) and quadriceps (TPTquad), and functional Hamstring-to-Quadriceps ratio (PTecc/PTcon).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 28, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 13, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 14, 2021

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 27, 2022

Completed
12 days until next milestone

First Posted

Study publicly available on registry

February 8, 2022

Completed
Last Updated

February 24, 2022

Status Verified

February 1, 2022

Enrollment Period

5 months

First QC Date

January 27, 2022

Last Update Submit

February 8, 2022

Conditions

Keywords

Isokinetic trainingpeak torqueacceleration timedeceleration timetime to peak torqueHamstring-to-Quadriceps ratio

Outcome Measures

Primary Outcomes (1)

  • Functional Hamstring-to-quadriceps ratio (PTecc:PTcon)

    This ratio was calculated using eccentric peak of hamstring and concentric peak torque of quadriceps muscle

    6 weeks

Secondary Outcomes (6)

  • Acceleration time of hamstring (AThams)

    6 weeks

  • Acceleration time of quadriceps

    6 weeks

  • Deceleration time of hamstring (DThams)

    6 weeks

  • Deceleration time of quadriceps

    6 weeks

  • Time to peak torque of hamstring

    6 weeks

  • +1 more secondary outcomes

Study Arms (2)

Eccentric isokinetic group

EXPERIMENTAL

In this group, eccentric isokinetic training of hamstring muscle was performed.

Other: Eccentric isokinetic training

Concentric isokinetic group

ACTIVE COMPARATOR

In this group, concentric isokinetic training of hamstring muscle was performed.

Other: Concentric isokinetic training

Interventions

Eccentric exercises of the hamstring muscles were performed with the use of an isokinetic dynamometer device.

Eccentric isokinetic group

Concentric exercises of the hamstring muscles were performed with the use of an isokinetic dynamometer device.

Concentric isokinetic group

Eligibility Criteria

Age18 Years - 28 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy young males
  • Age between 18 to 27
  • Recreationally active who used to engage regularly in 1-5 hours of physical activity per week

You may not qualify if:

  • Individual presently indulged in strength training of knee.
  • Individuals with any kind of injury around the knee, hip, ankle, foot
  • Unconsolidated fractures around the knee. • Stress fractures
  • Subjects with the acute phase of trauma, which may interfere with the exercise regime
  • Subjects with cardio-respiratory problems and other medical problems like diabetes, asthma, etc.
  • Subjects with tendinitis and other inflammatory conditions.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

King Saud University

Riyadh, 11433, Saudi Arabia

Location

Related Publications (1)

  • Sharma KN, Quddus N, Hameed UA, Khan SA, Kumari A, Alghadir AH, Khan M. Mode-specific effects of concentric and eccentric isokinetic training of the hamstring muscle at slow angular velocity on the functional hamstrings-to-quadriceps ratio-a randomized trial. PeerJ. 2022 Sep 29;10:e13842. doi: 10.7717/peerj.13842. eCollection 2022.

Study Officials

  • Masood Khan, M.P.Th

    King Saud University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Model Details: Participants were randomly divided into two groups.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 27, 2022

First Posted

February 8, 2022

Study Start

April 28, 2021

Primary Completion

September 13, 2021

Study Completion

October 14, 2021

Last Updated

February 24, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will not share

Locations