Relationship Between Hyperventilation Syndrome and SARS-CoV-2 Infection

NCT05224830 | Completed

• 1 other identifier: 2021PI224-203
• Study Type: observational
• Target: 2,846
• Locations: 1 country
• Sites: 1

Brief Summary

Following an acute COVID-19 infection, many patients suffer from long lasting physical symptoms that may greatly impair quality of life. Persisting dyspnea and other functional respiratory complaints could evoke Hyperventilation Syndrome (HVS) as a putative contributor of the long-COVID presentation in COVID-19 survivors. We aimed to assess the possible relationship between a HVS and previous acute SARS-CoV-2 infection.

Conditions

COVID-19; Hyperventilation Syndrome

Keywords

covid-19; dyspnea; Hyperventilation Syndrome

Outcome Measures

Primary Outcomes (1)

• Assess the relationship between a hyperventilation syndrome and previous acute SARS-CoV-2 infection.

  Nijmegen questionnaire during 15 minutes (cross-sectional monocentric study)

Secondary Outcomes (1)

• Assess the relationship between a hyperventilation syndrome and dyspnea

  Nijmegen questionnaire during 15 minutes (cross-sectional monocentric study)

Study Arms (2)

Presence of Hyperventilation Syndrome (HVS+)

Study population was divided into two groups according to the diagnosis of Hyperventilation Syndrome HVS +- : Nijmegen questionnaire score \> 23/64

Other: Nijmegen questionnaire score

No presence of Hyperventilation Syndrome (HVS-).

Study population was divided into two groups according to the diagnosis of Hyperventilation Syndrome HVS - : Nijmegen questionnaire score \< 24/64

Other: Nijmegen questionnaire score

Interventions

Nijmegen questionnaire score OTHER

We collected the Nijmegen Questionnaire in order to diagnosis of Hyperventilation Syndrome

No presence of Hyperventilation Syndrome (HVS-).; Presence of Hyperventilation Syndrome (HVS+)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The inclusion criteria were age greater than 18 years old, with the ability to perform a pulmonary function test in our Lung Function and Exercise Testing Department. Eligible patients were able to read and speak French in order to correctly answer to the self-reported questionnaire. The exclusion criteria were incomplete questionnaire or inability to obtain an interpretable lung function assessment.

You may qualify if:

• Read and speak French
• Perform a pulmonary function test

You may not qualify if:

• \- incomplete questionnaire or inability to obtain an interpretable lung function assessment

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Study Sites (1)

Centre Hospitalier Régional Universitaire de Nancy.

Vandœuvre-lès-Nancy, 54500, France

Location

MeSH Terms

Conditions

COVID-19; Dyspnea

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Respiration Disorders; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 3, 2022
• First Posted: February 4, 2022
• Study Start: January 1, 2021
• Primary Completion: May 1, 2022
• Study Completion: July 1, 2022
• Last Updated: September 7, 2022

Record last verified: 2022-02

Locations

FR (1)