Nutritional Follow up After Hospital Discharge for Coronavirus Disease-19

NCT04451694 | Unknown

• 1 other identifier: 2020PI097
• Study Type: observational
• Target: 800
• Locations: 1 country
• Sites: 1

Brief Summary

Coronavirus infection is responsible for muscle wasting (sarcopenia), especially during prolonged stays in intensive care. Sarcopenia, in its functional aspect also seems major in patients hospitalized for this infection, in non-ICU unit. Weight loss also appears to be significant, despite a prevalence of overweight and obesity in severe forms. Undernutrition in the obese patient is also possible (undernourished obese and sarcopenia obesity). Anosmia and dysgeusia participate in undernutrition by reducing energy intake. The rehabilitation of these patients requires nutritional support (increased protein intake) associated with progressive retraining to physical activity. An early and proactive management procedure within Coronavirus disease-19 units has been implemented in conjunction with the Transversal Nutrition Unit (TNU). This nutritional care must be continued after discharge. Follow-up by teleconsultation or telephone consultation is put in place after the patient's discharge Primary Objective: Evaluation of nutritional status at the time of admission and discharge and home follow-up in outgoing patients from Coronavirus disease-19 Units Secondary objectives: Description of the evolution of food intake, diversity of food and coverage of needs Evaluation of the muscular strength of the wrist (by grip test in hospital) and on the arms and legs after return home (visual analog scale) Evolution of anosmia and dysgeusia (at the time of hospital admission, at the time of hospital discharge and at home) Level of physical training before infection (IPAQ) Description of the general state of health measured by the performance index - world health organization scale Description of nutritional prescriptions Description of the prevention measures and incidence of Inappropriate Refeeding Syndrome (IRS) Care needs assessments

Conditions

Covid-19

Keywords

nutritional status; malnutrition; diet intervention; sarcopenia; muscle strength

Outcome Measures

Primary Outcomes (2)

• nutritional evaluation

  weight

  before Covid, at hospital discharge and between 7 and 45 days after discharge

• nutritional evaluation

  BMI

  before Covid, at at the time of hospital admission, at the time of hospital discharge and between 7 and 45 days after discharge

Secondary Outcomes (6)

• muscle strenght

  at the time of hospital admission and at the time of hospital discharge

• food intake

  at the time of hospital admission, at the time of hospital discharge

• food intake

  between 7 and 45 days after discharge

• muscle strenght

  between 7 and 45 days after discharge

• biological nutritional status

  at the time of hospital admission, at the time of hospital discharge

Study Arms (1)

Covid-19 unit outgoing patients

nutritional evaluation and intervention

Other: nutritional intervention

Interventions

nutritional intervention OTHER

nutritional evaluation and intervention and orientation towards adapted care establishment

Covid-19 unit outgoing patients

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

complete survey, about 800 patients. No sample List of patients discharged from COVID Units

You may qualify if:

• Covid positive (RT-PCR)

You may not qualify if:

• Unable to answer questions by telephone or teleconsultation directly or through a relative, minors under 16 years of age

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Study Sites (1)

Quilliot

Vandœuvre-lès-Nancy, 54500, France

RECRUITING

Related Publications (2)

• Treuil M, Mahmutovic M, Di Patrizio P, Nguyen-Thi PL, Quilliot D. Assessment of dynapenia and undernutrition in primary care, a systematic screening study in community medicine. Clin Nutr ESPEN. 2023 Oct;57:561-568. doi: 10.1016/j.clnesp.2023.08.003. Epub 2023 Aug 5.

  PMID: 37739706 DERIVED

• Quilliot D, Gerard M, Bonsack O, Malgras A, Vaillant MF, Di Patrizio P, Jaussaud R, Ziegler O, Nguyen-Thi PL. Impact of severe SARS-CoV-2 infection on nutritional status and subjective functional loss in a prospective cohort of COVID-19 survivors. BMJ Open. 2021 Jul 14;11(7):e048948. doi: 10.1136/bmjopen-2021-048948.

  PMID: 34261689 DERIVED

MeSH Terms

Conditions

COVID-19; Malnutrition; Sarcopenia

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Nutrition Disorders; Nutritional and Metabolic Diseases; Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 15, 2020
• First Posted: June 30, 2020
• Study Start: April 1, 2020
• Primary Completion: July 30, 2020
• Study Completion: November 30, 2020
• Last Updated: June 30, 2020

Record last verified: 2020-06

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)