COVID-19 and Vitamin D: Length of Hospital Stay and Mortality

NCT05221983 | Completed

• 1 other identifier: YuksekIU-SCOZBEK001
• Study Type: observational
• Target: 168
• Locations: 1 country
• Sites: 1

Brief Summary

The lack of a pharmacological treatment in the COVID-19 pandemic has pushed scientists to search for this issue. Maintaining optimal health is parallel to adequate and balanced nutrition. In this context, can the protective properties of vitamin D play an important role in this pandemic? brought with it the thought. In this study, it was aimed to examine the effect of vitamin D on mortality and hospital stay in COVID-19 disease.

Conditions

COVID-19 Pandemic; Vitamin D Deficiency

Keywords

COVID-19; Vitamin D; Length of stay; Mortality

Outcome Measures

Primary Outcomes (3)

• Level of Vitamin D

  Vitamin D levels of patients with a diagnosis of COVID-10. These results were categorized at the level of deficiency/insufficiency/normal.

  1 month later

• Relationship between vitamin D level and mortality

  Relationship between survival and death by categorized vitamin D level.

  1 month later

• Relationship between vitamin D level and hospital stay

  Length of hospital stay by categorized vitamin D level.

  1 month later

Secondary Outcomes (1)

• Effects of additional diseases (Diabetes mellitus, hypertension, etc.) on hospital stay and mortality

  1 month later.

Study Arms (1)

Patients with COVID-19 + with vitamin D levels

Patients with COVID-19 + and vitamin D levels were included in the study retrospectively. Vitamin D level was categorized into 3 groups as inadequacy, deficiency and normal from medical records. No intervention was made.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Adult patients with positive COVID-19 PCR (Polymerase Chain Reaction) test and vitamin D level in biochemical parameters, who applied to Ankara City Hospital Neurology-Orthopedics Hospital between 01 August and 31 October 2020.

You may qualify if:

• COVID-19 PCR (Polymerase Chain Reaction) test positive
• Vitamin D level in biochemical parameters
• Adult patients hospitalized for COVID-19

You may not qualify if:

• Patients using drugs that may affect vitamin D absorption, such as corticosteroids, cholesterol-lowering agents, phenobarbital and phenytoin-containing agents

Sponsors & Collaborators

• Yuksek Ihtisas University: lead
• Ankara City Hospital Bilkent: collaborator

Study Sites (1)

Republic of Turkey Ministry of Health Ankara City Hospitals Neurology-Orthopedics Hospital

Ankara, 06800, Turkey (Türkiye)

Location

MeSH Terms

Conditions

COVID-19; Vitamin D Deficiency

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Avitaminosis; Deficiency Diseases; Malnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases

Study Officials

• Levent Öztürk, MD

  Republic of Turkey Ministry of Health Ankara City Hospitals Neurology-Orthopedics Hospital

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: February 2, 2022
• First Posted: February 3, 2022
• Study Start: August 21, 2021
• Primary Completion: November 9, 2021
• Study Completion: November 16, 2021
• Last Updated: February 21, 2022

Record last verified: 2022-02

Locations

TU (1)