NCT05221918

Brief Summary

The purpose of this research is to find out more about detecting movement of CSF (fluid around the brain) with MRI. Researchers are doing this research study to find out how measurements of CSF movement differ among MRI machines and how image quality is changed by reducing the scan time.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 23, 2022

Completed
11 days until next milestone

First Posted

Study publicly available on registry

February 3, 2022

Completed
7 months until next milestone

Study Start

First participant enrolled

September 14, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 20, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 20, 2023

Completed
Last Updated

September 19, 2024

Status Verified

September 1, 2024

Enrollment Period

5 months

First QC Date

January 23, 2022

Last Update Submit

September 16, 2024

Conditions

Healthy

Outcome Measures

Primary Outcomes (2)

  • Comparison of flow metrics among scanners

    Flow metrics such as average total flow will be compared among multiple MRI scanners

    February -December 2022

  • Comparison of flow metrics between scans with and without parallel imaging

    Flow metrics such as the average total flow will be compared between sequences acquired with and without acceleration techniques, including parallel imaging, for a given scanner

    February -December 2022

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

The study population will include healthy young adults, ages 18-40 years.

You may qualify if:

  • \- A healthy volunteer will be defined as an otherwise healthy person who does not have a medical condition that affects brain function or have problems with concentration, memory, balance, or coordination.

You may not qualify if:

  • \- Subjects with non-MRI compatible devices, required sedation (claustrophobia or unable to remain still for exam), or women who are pregnant will be excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mayo Clinic

Rochester, Minnesota, 55905, United States

Location

Study Officials

  • Petrice Cogswell, MD, PhD

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 23, 2022

First Posted

February 3, 2022

Study Start

September 14, 2022

Primary Completion

February 20, 2023

Study Completion

February 20, 2023

Last Updated

September 19, 2024

Record last verified: 2024-09

Locations

US(1)