Blood Donation and Subjective Well-being

NCT05213130 | Completed

• 1 other identifier: Blood donation and well-being
• Study Type: interventional
• Target: 601
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates the psychological effects of blood donation among adult donors at the Guangzhou Blood Center. The primary objective is to examine whether a brief gratitude-based intervention delivered after donation enhances donors' subjective well-being (SWB) and basic psychological need (BPN) satisfaction. Participants who complete a whole-blood donation are randomly assigned to either an Intervention group, receiving a standardized gratitude reinforcement message accompanied by a vignette emphasizing the life-saving impact of donation, or a Control group that receives no additional message. All participants complete questionnaires at Time 1 (immediately after donation) and at Time 2 (4-22 days later), assessing SWB and related psychosocial variables.

Conditions

Happiness; Blood Donation

Outcome Measures

Primary Outcomes (1)

• Score of Subjective Well-Being at Time 2

  Subjective well-being (SWB) is assessed at follow-up using a validated multi-item measure capturing life satisfaction and affective well-being. Affect-Adjective Scale (validated Chinese version): 9 items, each scored 1-7. Satisfaction with Life Scale (validated Chinese version): 5 items scored 1-7. An aggregate SWB score was calculated by standardizing and summing life satisfaction scores with positive affect scores and subtracting the negative affect score from them. Scores range from low to high levels of well-being. The primary objective is to evaluate whether exposure to the gratitude-based intervention leads to higher SWB relative to the control condition.

  4-22 days after donation

Secondary Outcomes (6)

• Score of Subjective Well-being at Time 1

  Immediately after donation

• Score of Basic Psychological Needs Satisfaction at Time 1

  Immediately after donation

• Score of Basic Psychological Needs Satisfaction at Time 2

  4-22 days after donation

• Score of Blood Donation Intention at Time 1

  Immediately after donation

• Score of Blood Donation Intention Score at Time 2

  4-22 days after donation

Study Arms (2)

Gratitude-based intervention

EXPERIMENTAL

Participants in this group receive a standardized gratitude-based intervention immediately after completing whole-blood donation. The intervention consists of (1) a written gratitude reinforcement message acknowledging the donor's contribution and emphasizing the life-saving impact of their donation, and (2) a brief vignette illustrating how donated blood benefits patients in need. The purpose of this intervention is to enhance donors' subjective well-being and psychological need satisfaction by reinforcing their sense of autonomy, competence, and relatedness. Participants complete questionnaires at Time 1 (post-donation) and Time 2 (4-22 days later).

Other: Information

No Message

NO INTERVENTION

Participants in this group complete the standard post-donation procedure and receive no additional message or vignette. They complete the same questionnaires at Time 1 (post-donation) and Time 2 (4-22 days later) as the Intervention group. This arm serves as the comparison condition for evaluating the effect of the gratitude-based intervention on subjective well-being and related psychosocial outcomes.

Interventions

Information OTHER

A reminder to inform donors that their blood has saved patient's life in a questionnaire.

Gratitude-based intervention

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Successfully completed a whole-blood donation at the Guangzhou Blood Center during the study period.
• Able to read and understand the study materials and provide informed consent.
• Provided the correct answer to a control question in the questionnaire
• Provided their phone number.
• Donated blood was successfully supplied to the hospitals.

You may not qualify if:

• Whole blood donors with positive or suspicious serological results.

Sponsors & Collaborators

• Guangzhou Blood Center: lead

Study Sites (1)

Guangzhou Blood Center

Guangzhou, Guangdong, 510095, China

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior Investigator

Study Record Dates

• First Submitted: January 15, 2022
• First Posted: January 28, 2022
• Study Start: January 18, 2022
• Primary Completion: March 12, 2022
• Study Completion: March 16, 2022
• Last Updated: January 13, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)