NCT01278537

Brief Summary

The aims of this study are to investigate whether patient empowerment, including information and decision-aids adapted to the risk and the need of the elderly patient, can improve outcome in an evidence-based modular pathway in terms of

  • shortened hospital stay by a reduced postoperative complication rate and
  • quality of life in elderly patients compared to control patients receiving standard of care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
690

participants targeted

Target at P75+ for not_applicable cancer

Timeline
Completed

Started Feb 2011

Typical duration for not_applicable cancer

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 18, 2011

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 19, 2011

Completed
13 days until next milestone

Study Start

First participant enrolled

February 1, 2011

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2014

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2014

Completed
Last Updated

March 14, 2014

Status Verified

March 1, 2014

Enrollment Period

2.9 years

First QC Date

January 18, 2011

Last Update Submit

March 13, 2014

Conditions

Keywords

elderlycancer surgeryquality of lifeempowermentshared-decision

Outcome Measures

Primary Outcomes (2)

  • Length of hospital stay

    within the first month

  • Quality of life

    within the first year

Secondary Outcomes (5)

  • Readmission rate

    within the first three months

  • Short-term complications

    within the first months

  • Overall mortality

    within one year

  • Depression

    within the first year

  • Stress

    within the first month

Study Arms (2)

Empowerment, shared-decision making,

EXPERIMENTAL

Patients receive a booklet with informations. Assessment of health-related risk factors. Assessment of psychological and physical social support Delirium protection. Early mobilization.

Behavioral: Information

control group

NO INTERVENTION

Interventions

InformationBEHAVIORAL

Booklet, motivational interviewing, brief advice

Empowerment, shared-decision making,

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Patients aged 65 years and older with abdominal, thoracical or urogenital cancer scheduled for surgery
  • Offered patient information and written informed consent
  • Confirmed cancer diagnosis via histology
  • Mini Mental state \> 23
  • Life-expectance \> 2 months

You may not qualify if:

  • Participation in another trial according to the German Drug Law 7 days to and 7 days after the operation during the study
  • No informed consent
  • Emergency patients
  • Lacking willingness to save and hand out data within the study
  • Accommodation in an institution due to an official or judicial order
  • Concurrent malignancies
  • Insufficient knowledge of the German language

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Department of Anaesthesiology, Hospital of the Ludwig - Maximilians - University of Munich

München, München, 81377, Germany

Location

Evangelisches Geriatriezentrum Berlin gGmbH

Berlin, State of Berlin, 13347, Germany

Location

Department of Anesthesiology and Intensive Care Medicine, Campus Virchow-Klinikum and Campus Charité Mitte, Charité - Universitaetsmedizin Berlin

Berlin, 13353, Germany

Location

Related Publications (4)

  • Scholtz K, Borchers F, Morgeli R, Krampe H, Schmidt M, Eckardt-Felmberg R, von Dossow V, Sehouli J, Stief CG, Pohrt A, Spies CD; PERATECS Group. Self-reported exhaustion and a 4-item physical frailty index to predict the incidence of major complications after onco-geriatric surgery. Eur J Surg Oncol. 2024 Jul;50(7):108421. doi: 10.1016/j.ejso.2024.108421. Epub 2024 May 23.

  • Mueller A, Spies CD, Eckardt R, Weiss B, Pohrt A, Wernecke KD, Schmidt M; PERATECS-Group. Anticholinergic burden of long-term medication is an independent risk factor for the development of postoperative delirium: A clinical trial. J Clin Anesth. 2020 May;61:109632. doi: 10.1016/j.jclinane.2019.109632. Epub 2019 Oct 24.

  • Scholtz K, Spies CD, Morgeli R, Eckardt R, von Dossow V, Braun S, Sehouli J, Bahra M, Stief CG, Wernecke KD, Schmidt M; PERATECS Group. Risk factors for 30-day complications after cancer surgery in geriatric patients: a secondary analysis. Acta Anaesthesiol Scand. 2018 Apr;62(4):451-463. doi: 10.1111/aas.13067. Epub 2018 Jan 22.

  • Schmidt M, Eckardt R, Scholtz K, Neuner B, von Dossow-Hanfstingl V, Sehouli J, Stief CG, Wernecke KD, Spies CD; PERATECS Group. Patient Empowerment Improved Perioperative Quality of Care in Cancer Patients Aged >/= 65 Years - A Randomized Controlled Trial. PLoS One. 2015 Sep 17;10(9):e0137824. doi: 10.1371/journal.pone.0137824. eCollection 2015.

MeSH Terms

Conditions

NeoplasmsEmpowerment

Condition Hierarchy (Ancestors)

Social BehaviorBehavior

Study Officials

  • Claudia Spies, MD Prof.

    Department of Anesthesiology and Intensive Care Medicine, Campus Virchow-Klinikum and Campus Charité Mitte, Charité - Universitaetsmedizin Berlin

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Univ. Prof. Dr. med. Claudia Spies

Study Record Dates

First Submitted

January 18, 2011

First Posted

January 19, 2011

Study Start

February 1, 2011

Primary Completion

January 1, 2014

Study Completion

February 1, 2014

Last Updated

March 14, 2014

Record last verified: 2014-03

Locations