NCT04484896

Brief Summary

Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. On July 22, 2020 blood stockpile of O-negative and A-negative in Guangzhou Blood Center reached the warning line, and we took measures for emergency recruitment. O-negative and A-negative blood donors whose last donation dates were between January 1, 2018 and December 31, 2019 were identified and randomly assigned to four groups. Three different recruitment text messages were send three groups. We observed the re-donation rates among four groups within one week.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,082

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2020

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 21, 2020

Completed
1 day until next milestone

Study Start

First participant enrolled

July 22, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 24, 2020

Completed
5 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 29, 2020

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2020

Completed
Last Updated

July 28, 2020

Status Verified

July 1, 2020

Enrollment Period

7 days

First QC Date

July 21, 2020

Last Update Submit

July 24, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Re-donation rate

    Intention-to-treat were applied. Re-donation rate was defined as the number of donors in each group divided by donors who re-donated within 7 days.

    7 days

Study Arms (4)

Gain-frame Message

EXPERIMENTAL

Short messaging service (SMS) message: Dear group O/A Rh-D negative blood donor: Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to save lives. Thank you for your support. Please bring your identification (ID) card and show this message to our staff. Thank you.

Other: Gain-framed SMS message

Loss-frame Message

EXPERIMENTAL

SMS message: Dear group O/A Rh-D negative blood donor: Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to prevent the loss of life. Thank you for your support. Please bring your ID card and show this message to our staff. Thank you.

Other: Loss-framed SMS message

Information Message

EXPERIMENTAL

SMS message: Dear group O/A Rh-D negative blood donor: Hello! The inventory of group O/A Rh-D negative blood product is low at present, if you can, please consider donating blood again. Thank you for your support. Please bring your ID card and show this message to our staff. Thank you.

Other: Information SMS message

Control group

NO INTERVENTION

Donors in this group were not received SMS reminders.

Interventions

Emergency recruitment cell phone short messages that emphasizing donating blood can save patients' lives were sent to donors in this group.

Gain-frame Message

Emergency recruitment cell phone short messages emphasizing that donating blood can prevent patients from death were sent to donors in this group.

Loss-frame Message

Emergency recruitment cell phone short messages that only mentioning the low Rh-negative blood stockpile were sent to donors in this group.

Information Message

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • \- O and A Rh- negative blood donors Last donations were between January 1, 2018 and December 31, 2019

You may not qualify if:

  • \- With an obviously invalid phone number Serological results of the last donation were positive

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Guangzhou Blood Center

Guangzhou, Guangdong, 510095, China

RECRUITING

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Participant did not know the difference between the three message.
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 21, 2020

First Posted

July 24, 2020

Study Start

July 22, 2020

Primary Completion

July 29, 2020

Study Completion

July 30, 2020

Last Updated

July 28, 2020

Record last verified: 2020-07

Locations