NCT05212441

Brief Summary

This study will be done to evaluate effect of applying LED before hand exercise on hand grip strength. Sixty male patients with subacute partial thickness burn of hand will be randomly allocated into two equal groups of 30 patients. The following equipment and tools will be used Measurement equipments:

  • For total active motion of fingers (TAM): Goniometer.
  • For hand grip strength: Hand grip dynamometer. Therapeutic equipment: Light emitting diode therapy (LED) device.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 15, 2022

Completed
13 days until next milestone

First Posted

Study publicly available on registry

January 28, 2022

Completed
28 days until next milestone

Study Start

First participant enrolled

February 25, 2022

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2022

Completed
9 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 10, 2022

Completed
Last Updated

May 10, 2022

Status Verified

May 1, 2022

Enrollment Period

4 months

First QC Date

January 15, 2022

Last Update Submit

May 6, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • Changes in Total active ROM from baseline to 6 weeks posttreatment

    Total active ROM is the sum of the active metacarpophalangeal (MP), proximal interphalangeal (PIP), and distal interphalangeal (DIP) arc of motion in degrees of an individual digit. The measurement will be performed via a hand-held finger goniometer

    baseline and 6 weeks posttreatment

  • Changes in hand grip strength from baseline to 6 weeks posttreatment

    A calibrated hydraulic JAMAR (Model: 5030J1, Sammons Preston Rolyan, Chicago, USA), analogue hand-grip dynamometer will be used to measure grip strength. The device provides 1 kg increments on the measurement dial which faces the assessor as mentioned by Clifford et al., 2013.

    baseline and 6 weeks posttreatment

Study Arms (2)

Group A (LED group)

EXPERIMENTAL

This group includes 30 burned patients who will receive LED therapy in addition to their physical therapy program (splinting, stretching ex., strengthening ex. and ROM ex.) and medical treatment.

Device: Light emitting diode therapy (LED therapy)Behavioral: Patient/family education program (Home program)Procedure: Positioning & SplintingOther: Therapeutic Exercises

Group B (Control group)

ACTIVE COMPARATOR

This group includes 30 burned patients who will receive their physical therapy program (splinting, stretching ex., strengthening ex. and ROM ex.) and medical treatment.

Behavioral: Patient/family education program (Home program)Procedure: Positioning & SplintingOther: Therapeutic Exercises

Interventions

The patient's forearm is positioned on table with palm facuing upward during the therapy. For LEDT, the center of the light spot located at approximately 50% of landmark line from the medial epicondyle to the styloid process of the ulna, which is the center belly of flexor digitorum superficialis. The subject's forearm maintained in the rest state without moving during the therapy. LED is performed before exercise.

Group A (LED group)

Patients and their families will instructed to learn the anti contracture positioning/splinting, scar massage and exercises program, application of the custom garments and inserts, and functional training to perform them on their own at home. Written and illustrative instructions and reciprocal demonstration sessions will be provided to the children and their families to ensure successful acquisition and delivery of rehabilitation skills at home program. The therapist will be reported about compliance with the home program every couple of days

Group A (LED group)Group B (Control group)

The wrist joint is splinted at 30 hyperextension, the MCP joint in 90 of flexion, the IP joints in extension, and the thumb in abduction. The webs of fingers kept in abduction. The hands are elevated above the level of the heart to minimize post-burn edema. Splinting: Splints are tailored to help to maintain the functional or anti-contracture position of the injured body parts.The intervals for monitoring vary from once every hour to once every 4-6 hours, depending on types of splints and skin conditions. It is described as 10 hours on and two hours off. When the splint is taken off, active and/or passive ROM should be carried out.

Group A (LED group)Group B (Control group)

1. Passive ROM (PROM). 2. Active ROM (AROM) \& Active-assistive ROM (AAROM): The exercise will focus on extending the wrist to 45 degrees, flexing the MCP joints to 90 degrees and keeping the IP joints in full extension, while maintaining a thumb web space. The exercises will performed in the following sequences; (1) MCP joints flexion and extension with the wrist in neutral or slight extension and the IP joints in neutral position. (2) IP joints flexion to only 30-40 degrees with the wrist stabilized in the neutral or slight extension, while the MCP joints held in full extension, (3) thumb and fingers abduction and adduction, and (4) thumb opposition (tip of the thumb to tip of the small finger). Each exercise was performed for 8-10 repetition, daily, for 6 days/week. 3. Stretching exercises: A low-load (low-intensity), long-duration stretch 4. Strengthening exercises: done in static mode initially and progress to dynamic strengthening using elastic bands.

Group A (LED group)Group B (Control group)

Eligibility Criteria

Age20 Years - 35 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • The subject selection will be according to the following criteria:
  • Burn caused by thermal injury (flame or scald) with involvement of the wrist and hand and other parts of the body not including shoulder and elbow.
  • Age range between 20-35 years.
  • Male gender.
  • Subacute Partial-thickness burn " From 3rd day of burn".
  • Recent discharge of in patient acute care, spontaneous healing.
  • All patients enrolled to the study will have their informed consent.

You may not qualify if:

  • The potential participants will be excluded if they meet one of the following criteria:
  • Cardiac diseases.
  • Perception of persistent respiratory problem related to a previous inhalation injury
  • Signs of burn infection (i.e., unclear fluid oozing from the wound, increased pain, expanded redness and swelling)
  • Exposed tendons.
  • Nerve, muscle injury.
  • Scar contracture of hand.
  • Cognitive disorders.
  • Presence of fractures.
  • Patients who suffer from skin diseases, diabetes, varicose veins, and peripheral vascular diseases.
  • Patients with life threatening disorders as renal failure, myocardial infarction or other similar diseases will be excluded from the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

October 6 University Hospital

Al Ḩayy Ath Thāmin, Giza Governorate, 12611, Egypt

Location

MeSH Terms

Conditions

BurnsHand Injuries

Interventions

Patient PositioningExercise Therapy

Condition Hierarchy (Ancestors)

Wounds and Injuries

Intervention Hierarchy (Ancestors)

Patient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and ServicesRehabilitationAftercareContinuity of Patient CarePhysical Therapy Modalities

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

January 15, 2022

First Posted

January 28, 2022

Study Start

February 25, 2022

Primary Completion

July 1, 2022

Study Completion

July 10, 2022

Last Updated

May 10, 2022

Record last verified: 2022-05

Locations