Aerobic Versus Resistance Exercises on Liver Enzymes Following Burn Injuries

NCT04365296 | Completed

• 1 other identifier: P.T.REC/012/002230
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

1. 1.Subjects:
2. 2.Equipment and tools:

Conditions

Burns

Outcome Measures

Primary Outcomes (1)

• Measures of AST and ALT Liver enzymes post treatment

  Measures of AST and ALT Liver enzymes post 8 weeks of treatment for 10 patients of Aerobic group and 10 patients of resistance group.

  2 months

Study Arms (2)

Aerobic group

EXPERIMENTAL

This group will include 30 burned patients who will receive aerobic exercises 8 weeks (3times/week) in form of treadmill exercise in addition to their physical therapy program (splinting, stretching ex. and ROM ex.) and medical treatment (medications as cataflam, alphintern, zinetac and hemacaps and wound dressings).

Other: Experimental

Resistance group

EXPERIMENTAL

This group will include 30 burned patients who will receive resistance exercises 8 weeks (3times/week) by using dumbbells and sand bags in addition to their physical therapy program (splinting, stretching ex. and ROM ex.) and medical treatment (medications as cataflam, alphintern, zinetac and hemacaps and wound dressings).

Other: Experimental

Interventions

Experimental OTHER

The purpose of the study is to evaluate which is more effective aerobic or resistance exercises in reducing plasma liver enzymes level (AST and ALT) post burn. Subjects and Methods: Sixty burned patients with burned body surface area about 30% to 50% will participate in this study. Their ages will be ranged from 20-45 years. They will be selected from Orabi Hospital and will be divided randomly into two equal groups.

Aerobic group; Resistance group

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• The subject selection will be according to the following criteria:
• Age range between 20-45 years.
• Male and female patients will participate in the study.
• All patients have burn with BBSA about 30% to 50%.
• All patients enrolled to the study will have their informed consent.

You may not qualify if:

• The potential participants will be excluded if they meet one of the following criteria:
• Cardiac diseases.
• Burn of sole of foot.
• Exposed hand or foot tendons.
• Lower limb amputation.
• History of liver diseases.
• Body mass index (BMI=kg/cm2)\<30%.

Sponsors & Collaborators

• Aya Gamal Fawzy El-Sayed: lead

Study Sites (1)

Orabi Hospital

Cairo, 11828, Egypt

Location

MeSH Terms

Conditions

Burns

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• A M Abd El Baky, Prof.DR

  Cairo University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant lecturer

Study Record Dates

• First Submitted: April 23, 2020
• First Posted: April 28, 2020
• Study Start: March 15, 2019
• Primary Completion: June 15, 2019
• Study Completion: March 15, 2020
• Last Updated: April 28, 2020

Record last verified: 2020-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)