NCT05208008

Brief Summary

The study aims to investigate the effects of a service dog on military veterans with post traumatic stress syndrome (PTSD). The investigators will use non-invasive measures of the physiological responses, data obtained via dairy keeping, accelerometer data estimating activity and sleep patterns, and baseline information including psychological measures validated for this specific population.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 20, 2021

Completed
28 days until next milestone

Study Start

First participant enrolled

January 17, 2022

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 26, 2022

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2024

Completed
Last Updated

May 8, 2024

Status Verified

May 1, 2023

Enrollment Period

2 years

First QC Date

December 20, 2021

Last Update Submit

May 7, 2024

Conditions

Keywords

Human-animal contactNon-invasive measure

Outcome Measures

Primary Outcomes (86)

  • Daily activity pattern

    Daily activity pattern measured with a wrist-worn accelerometer

    In the experimental period, which is 14 days

  • Sleep pattern

    Sleep pattern measured with a wrist-worn accelerometer

    In the experimental period, which is 14 days

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 1 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 1 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 2 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 2 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 3 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 3 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 4 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 4 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 5 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 5 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 6 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 6 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 7 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 7 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 8 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 8 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 9 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 9 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 10 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 10 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 11 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 11 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 12 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 12 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 13 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 13 of the experimental period at 8 p.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 14 of the experimental period at 11 a.m.

  • Salivary, Cortisol

    Saliva is obtained from the testperson with a cotton swab which is chewed for one minute

    Day 14 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 1 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 1 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 2 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 2 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 3 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 3 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 4 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 4 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 5 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 5 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 6 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 6 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 7 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 7 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 8 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 8 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 9 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 9 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 10 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 10 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 11 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 11 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 12 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 12 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 13 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 13 of the experimental period at 8 p.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 14 of the experimental period at 11 a.m.

  • Blood pressure

    Blood pressure is measured manually with a blood pressure monitor with a blood pressure cuff

    Day 14 of the experimental period at 8 p.m.

  • Heart rate

    The test person wears either self-adhesive electrodes or a belt around their chest and the heart rate is measured non-invasively

    Day 2 of the experimental period

  • Heart rate

    The test person wears either self-adhesive electrodes or a belt around their chest and the heart rate is measured non-invasively

    Day 4 of the experimental period

  • Heart rate

    The test person wears either self-adhesive electrodes or a belt around their chest and the heart rate is measured non-invasively

    Day 6 of the experimental period

  • Heart rate

    The test person wears either self-adhesive electrodes or a belt around their chest and the heart rate is measured non-invasively

    Day 8 of the experimental period

  • Heart rate

    The test person wears either self-adhesive electrodes or a belt around their chest and the heart rate is measured non-invasively

    Day 10 of the experimental period

  • Heart rate

    The test person wears either self-adhesive electrodes or a belt around their chest and the heart rate is measured non-invasively

    Day 12 of the experimental period

  • Heart rate

    The test person wears either self-adhesive electrodes or a belt around their chest and the heart rate is measured non-invasively

    Day 14 of the experimental period

  • Heart rate variability

    Heart rate variability is calculated from heart rate data

    Day 2 of the experimental period

  • Heart rate variability

    Heart rate variability is calculated from heart rate data

    Day 4 of the experimental period

  • Heart rate variability

    Heart rate variability is calculated from heart rate data

    Day 6 of the experimental period

  • Heart rate variability

    Heart rate variability is calculated from heart rate data

    Day 8 of the experimental period

  • Heart rate variability

    Heart rate variability is calculated from heart rate data

    Day 10 of the experimental period

  • Heart rate variability

    Heart rate variability is calculated from heart rate data

    Day 12 of the experimental period

  • Heart rate variability

    Heart rate variability is calculated from heart rate data

    Day 14 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 1 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 2 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 3 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 4 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 5 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 6 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 7 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 8 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 9 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 10 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 11 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 12 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 13 of the experimental period

  • Dairy notes regarding stressful events

    The participant notes whether any situations, perceived to be stressful has happened, during each of the 14 days in the experimental peiod.during the experimental period

    Day 14 of the experimental period

Study Arms (2)

With service dog

Veterans living with a certified service dog

Other: With service dog

Without service dog

Veterans living without a certified service dog

Interventions

No intervention

With service dog

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Military veterans, that either already ave a certified service dog, or are approved to receive a certified service dog, but on a waitlist. Furthermore, the military veterans should fulfill the inclusion criteria. The are recruited with help from the Danish Military, and the initial contact is established when potential participants respond to the advertisements by contacting of the scientific staff of the project.

You may qualify if:

  • Have been deployed in a war zone
  • Fulfil criteria for PTSD
  • Fulfil criteria for receiving a certified service dog
  • If having a service dog, they must have owned the dog for more than 6 months, and the dog must be at leat 2 years of age

You may not qualify if:

  • Use of alcohol or drugs to an extent that it affects the ability to attend to ordinary daily activities

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Karen Thodberg

Højslev, 7840, Denmark

Location

MeSH Terms

Conditions

Sleep Disorders, Circadian RhythmStress, Psychological

Condition Hierarchy (Ancestors)

Chronobiology DisordersNervous System DiseasesDyssomniasSleep Wake DisordersOccupational DiseasesMental DisordersBehavioral SymptomsBehavior

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 20, 2021

First Posted

January 26, 2022

Study Start

January 17, 2022

Primary Completion

December 31, 2023

Study Completion

December 31, 2024

Last Updated

May 8, 2024

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will not share

Locations