Report of the Survival Outcomes of Patients With Esophageal Cancer After Definitive Radiotherapy in China

NCT05194371 | Completed

• 1 other identifier: YW2021-92-1
• Study Type: observational
• Target: 3,000
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, data of esophageal cancer patients undergoing definitive radiotherapy in 14 institutions from various provinces in China were evaluated to help strengthen confidence in anti-cancer, including rehabilitation, economic burden, and quality of life.

Conditions

Esophageal Neoplasms

Outcome Measures

Primary Outcomes (1)

• Overall survival

  5 year

Secondary Outcomes (3)

• the European Organisation for Research and Treatment of Cancer (EORTC) questionnaire module to assess quality of life (QOL)

  5 year

• Costs of treatment

  5 year

• Proportion of using chemotherapy or target therapy concurrently with radiotherapy

  2 month

Study Arms (1)

Definitive (chemo)radiotherapy

Radiation: definitive radiotherapy or definitive chemoradiotherapy

Interventions

definitive radiotherapy or definitive chemoradiotherapy RADIATION

A total dose of radiation therapy should be more than 50Gy

Definitive (chemo)radiotherapy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with esophageal cancer who received definitive radiotherapy (radiotherapy dose ≥50Gy) from 2015 to 2016 in 14 institutions in China

You may qualify if:

• Patients with esophageal cancer who received definitive radiotherapy (radiotherapy dose ≥50Gy) from 2015 to 2016
• Age ≥ 18
• The radiation field included primary esophageal tumor with or without lymph node metastasis

You may not qualify if:

• Radiotherapy dose \< 50Gy
• Palliative radiotherapy
• The radiation field are metastatic areas, such as bone, brain, adrenal gland, isolated metastatic lymph nodes, etc

Sponsors & Collaborators

• Chinese Academy of Medical Sciences: lead

Study Sites (1)

Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC)

Beijing, 100021, China

Location

MeSH Terms

Conditions

Esophageal Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Head and Neck Neoplasms; Digestive System Diseases; Esophageal Diseases; Gastrointestinal Diseases

Study Officials

• Lvhua Wang

  National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medic

  PRINCIPAL INVESTIGATOR

• Kuaile Zhao

  Fudan University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 24, 2021
• First Posted: January 18, 2022
• Study Start: June 1, 2021
• Primary Completion: October 31, 2021
• Study Completion: December 15, 2021
• Last Updated: January 18, 2022

Record last verified: 2022-01

Locations

CN (1)