NCT05180448

Brief Summary

Adults attempting weight loss through lifestyle modification (LM) typically find maintenance of behavior change difficult. Outcomes might be improved if participants are provided with sustained sources of accountability and support and ongoing opportunities to reflect with others on goal progress. This study proposes that sharing digital data with other parties has the potential to improve long-term weight loss. The proposed study will enroll adults ("index participants") (N = 320) with overweight/obesity in a 24-month LM program and instruct them to use digital tools for self-monitoring of weight, physical activity, and eating on a daily basis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
322

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 20, 2021

Completed
4 months until next milestone

Study Start

First participant enrolled

January 3, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 6, 2022

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2025

Completed
Last Updated

September 30, 2025

Status Verified

September 1, 2025

Enrollment Period

3.6 years

First QC Date

September 20, 2021

Last Update Submit

September 24, 2025

Conditions

Keywords

weight losslifestyle modificationbehavioral modificationoverweightobesity

Outcome Measures

Primary Outcomes (1)

  • Weight

    Weight will be measured using a wireless scale. In order to maximize accuracy, we will (1) provide instructions (e.g., place scale on flat, hard surface; weigh upon waking, without clothes, after using the bathroom), (2) require participants to confirm that they are following instructions at each assessment point, (3) remove errant weights (e.g., \>1 kg change in 1 day).

    0 month, 3 month, 6 month, 12 month, 24 month

Secondary Outcomes (2)

  • Physical Activity

    0 month, 3 month, 6 month, 12 month, 24 month

  • Calorie Intake

    0 month, 3 month, 6 month, 12 month, 24 month

Other Outcomes (12)

  • Perceived Supportive Accountability for Weight Control

    0 months, 6 month, 12 month, 24 month

  • Self-regulation value of program components

    3 months, 6 month, 12 month, 24 month

  • Self-monitoring

    Calculated continuously for 24 months

  • +9 more other outcomes

Study Arms (8)

Coach Share On + Group Share On + Friend/Family Share On

EXPERIMENTAL
Behavioral: Coach Share OnBehavioral: Group Share OnBehavioral: Friend/Family Share OnBehavioral: Behavioral Weight Loss Treatment

Coach Share On + Group Share On + Friend/Family Share Off

EXPERIMENTAL
Behavioral: Coach Share OnBehavioral: Group Share OnBehavioral: Friend/Family Share OffBehavioral: Behavioral Weight Loss Treatment

Coach Share On + Group Share Off + Friend/Family Share On

EXPERIMENTAL
Behavioral: Coach Share OnBehavioral: Friend/Family Share OnBehavioral: Group Share OffBehavioral: Behavioral Weight Loss Treatment

Coach Share On + Group Share Off + Group Share Off

EXPERIMENTAL
Behavioral: Coach Share OnBehavioral: Group Share OffBehavioral: Friend/Family Share OffBehavioral: Behavioral Weight Loss Treatment

Coach Share Off + Group Share On + Friend/Family Share On

EXPERIMENTAL
Behavioral: Group Share OnBehavioral: Friend/Family Share OnBehavioral: Coach Share OffBehavioral: Behavioral Weight Loss Treatment

Coach Share Off + Group Share On + Friend/Family Share Off

EXPERIMENTAL
Behavioral: Group Share OnBehavioral: Coach Share OffBehavioral: Friend/Family Share OffBehavioral: Behavioral Weight Loss Treatment

Coach Share Off + Group Share Off + Friend/Family Share On

EXPERIMENTAL
Behavioral: Friend/Family Share OnBehavioral: Coach Share OffBehavioral: Group Share OffBehavioral: Behavioral Weight Loss Treatment

Coach Share Off + Group Share Off + Friend/Family Share Off

EXPERIMENTAL
Behavioral: Coach Share OffBehavioral: Group Share OffBehavioral: Friend/Family Share OffBehavioral: Behavioral Weight Loss Treatment

Interventions

Coach Share OnBEHAVIORAL

If an index participant is randomized to have Coach Share ON, the coach will have continuous access to objective, real-time, detailed device data, and address data directly in all individual interactions with index participants (groups, individual weigh-ins, phone calls, texts), conveying that they are closely monitoring progress.

Coach Share On + Group Share Off + Friend/Family Share OnCoach Share On + Group Share Off + Group Share OffCoach Share On + Group Share On + Friend/Family Share OffCoach Share On + Group Share On + Friend/Family Share On
Group Share OnBEHAVIORAL

If Group Share is ON, participants in a given LM group will view and respond to aspects of each other's self-monitoring device data in their small-group text messages. Each small group participant's data will be highlighted one day of the month, and content from the Group Share Off message library also will be sent.

Coach Share Off + Group Share On + Friend/Family Share OffCoach Share Off + Group Share On + Friend/Family Share OnCoach Share On + Group Share On + Friend/Family Share OffCoach Share On + Group Share On + Friend/Family Share On

Index participants who are randomized to have Friend/Family Share ON will give their friend or family member access to their self-monitoring data. Text messages sent by the program bot, which includes the index participant and friend/family member, will use a similar format as described in Group Share ON. The friend or family member will be trained to respond to data in ways that enhance the participant's motivation and self-regulation.

Coach Share Off + Group Share Off + Friend/Family Share OnCoach Share Off + Group Share On + Friend/Family Share OnCoach Share On + Group Share Off + Friend/Family Share OnCoach Share On + Group Share On + Friend/Family Share On
Coach Share OffBEHAVIORAL

Among index participants who are randomized to have Coach Share OFF, the coach will have no access to their device data. Index participants will be explicitly told their coach does not have data access. During groups and phone calls, the participant will self-report progress, and goal setting will be based on that self-report. Text messages from the coach will be personalized in the OFF condition, as they are when coach data sharing is ON, though these messages will not be informed by device data. Instead, text messages will provide a reminder of key goals and strategies discussed in the previous phone call and provide encouragement for participant efforts.

Coach Share Off + Group Share Off + Friend/Family Share OffCoach Share Off + Group Share Off + Friend/Family Share OnCoach Share Off + Group Share On + Friend/Family Share OffCoach Share Off + Group Share On + Friend/Family Share On
Group Share OffBEHAVIORAL

Among index participants randomized to have Group Share OFF, supportive accountability will not be the target of participant interactions and no data will be shared with LM program peers. Instead, once weekly prompts for small group text exchanges will encourage index participants to provide social support (primarily of the informational type) to each other. Index participants will be explicitly told that they should not include information on goal progress such as weight change or minutes of PA.

Coach Share Off + Group Share Off + Friend/Family Share OffCoach Share Off + Group Share Off + Friend/Family Share OnCoach Share On + Group Share Off + Friend/Family Share OnCoach Share On + Group Share Off + Group Share Off

If an index participant is randomized to Friend/Family Share OFF, the text messages from the bot will prompt the participant and friend/family member to communicate about the LM program; those messages will be standardized, except for names, and will not be tailored to index participant progress. Index participants will be instructed to refrain from sharing any device data with friends or family members.

Coach Share Off + Group Share Off + Friend/Family Share OffCoach Share Off + Group Share On + Friend/Family Share OffCoach Share On + Group Share Off + Group Share OffCoach Share On + Group Share On + Friend/Family Share Off

Standard Behavioral Weight Loss Treatment (remotely delivered)

Coach Share Off + Group Share Off + Friend/Family Share OffCoach Share Off + Group Share Off + Friend/Family Share OnCoach Share Off + Group Share On + Friend/Family Share OffCoach Share Off + Group Share On + Friend/Family Share OnCoach Share On + Group Share Off + Friend/Family Share OnCoach Share On + Group Share Off + Group Share OffCoach Share On + Group Share On + Friend/Family Share OffCoach Share On + Group Share On + Friend/Family Share On

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Individuals must be of overweight or obese BMI (27-50 kg/m2)
  • Individuals must be adults (aged 18-70)
  • Able to engage in physical activity (defined as walking two city blocks without stopping)
  • Access and willingness to use a smartphone and internet
  • Has one adult friend or family member who indicates willingness to serve in a support role
  • Satisfactory completion of all enrollment procedures
  • English Speaking

You may not qualify if:

  • Medical or psychiatric condition (e.g., cancer, type I diabetes, psychosis, full-threshold eating disorder) that may pose a risk to the participant during intervention or cause a change in weight, or limit ability to comply with the program or participate appropriately in group-based treatment
  • Currently pregnant or breastfeeding, or planning to become pregnant in the next 24 months
  • Use of insulin or a medication that can cause significant change in weight
  • History of bariatric surgery
  • Weight loss of greater than or equal to 5% in the previous 3 months
  • Weight loss of greater than or equal to 10% in the past 3 years that is currently being maintained

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Drexel University

Philadelphia, Pennsylvania, 19104, United States

Location

MeSH Terms

Conditions

OverweightObesityWeight Loss

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBody Weight Changes

Study Officials

  • Meghan L Butryn, PhD

    Drexel University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Outcomes assessors will be blind to condition.
Purpose
TREATMENT
Intervention Model
FACTORIAL
Model Details: This is a 2x2x2 design. There are three factors, each with two levels: ON vs OFF
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 20, 2021

First Posted

January 6, 2022

Study Start

January 3, 2022

Primary Completion

July 30, 2025

Study Completion

July 30, 2025

Last Updated

September 30, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Locations