NCT05175144

Brief Summary

This study aims to evaluate whether EDACS performed during triage to assess patients with chest pain could improve the predictive validity of triage for an acute cardiovascular event.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
146

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2022

Typical duration for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 14, 2021

Completed
20 days until next milestone

First Posted

Study publicly available on registry

January 3, 2022

Completed
11 months until next milestone

Study Start

First participant enrolled

December 1, 2022

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2024

Completed
1.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2025

Completed
Last Updated

August 2, 2022

Status Verified

July 1, 2022

Enrollment Period

1.1 years

First QC Date

December 14, 2021

Last Update Submit

July 29, 2022

Conditions

Acute Chest Pain

Outcome Measures

Primary Outcomes (1)

  • Diagnostic performance of EDACS for detection of acute cardiovascular events in emergency department.

    baseline

Secondary Outcomes (1)

  • Baseline characteristics for patients with acute cardiovascular events.

    baseline

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Any patient fulfilling the inclusion criteria can participating in our study . .

You may qualify if:

  • Patients \>18 years old who admitted to ED complaining of chest pain.
  • Chest pain is considered to be an acute chest pain, described as pain, pressure, tightness, or burning as outlined in the guidelines.
  • Chest pain equivalent symptoms may include dyspnea, epigastric pain, and pain in the left arm.

You may not qualify if:

  • Patients unable to complete the EDACS
  • Posttraumatic chest pain
  • Patients who did not give consent to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (7)

  • Niska R, Bhuiya F, Xu J. National Hospital Ambulatory Medical Care Survey: 2007 emergency department summary. Natl Health Stat Report. 2010 Aug 6;(26):1-31.

    PMID: 20726217BACKGROUND

  • Bayon Fernandez J, Alegria Ezquerra E, Bosch Genover X, Cabades O'Callaghan A, Iglesias Garriz I, Jimenez Nacher JJ, Malpartida De Torres F, Sanz Romero G; Grupo de Trabajo ad hoc de la Seccion de Cardiopatia Isquemica y Unidades Coronarias de la Sociedad Espanola de Cardiologia. [Chest pain units. Organization and protocol for the diagnosis of acute coronary syndromes]. Rev Esp Cardiol. 2002 Feb;55(2):143-54. doi: 10.1016/s0300-8932(02)76574-3. Spanish.

    PMID: 11852005BACKGROUND

  • Hinson JS, Martinez DA, Cabral S, George K, Whalen M, Hansoti B, Levin S. Triage Performance in Emergency Medicine: A Systematic Review. Ann Emerg Med. 2019 Jul;74(1):140-152. doi: 10.1016/j.annemergmed.2018.09.022. Epub 2018 Nov 22.

    PMID: 30470513BACKGROUND

  • Zaboli A, Ausserhofer D, Sibilio S, Toccolini E, Bonora A, Giudiceandrea A, Rella E, Paulmichl R, Pfeifer N, Turcato G. Effect of the Emergency Department Assessment of Chest Pain Score on the Triage Performance in Patients With Chest Pain. Am J Cardiol. 2021 Dec 15;161:12-18. doi: 10.1016/j.amjcard.2021.08.058. Epub 2021 Oct 9.

    PMID: 34635312BACKGROUND

  • Than M, Flaws D, Sanders S, Doust J, Glasziou P, Kline J, Aldous S, Troughton R, Reid C, Parsonage WA, Frampton C, Greenslade JH, Deely JM, Hess E, Sadiq AB, Singleton R, Shopland R, Vercoe L, Woolhouse-Williams M, Ardagh M, Bossuyt P, Bannister L, Cullen L. Development and validation of the Emergency Department Assessment of Chest pain Score and 2 h accelerated diagnostic protocol. Emerg Med Australas. 2014 Feb;26(1):34-44. doi: 10.1111/1742-6723.12164. Epub 2014 Jan 15.

    PMID: 24428678BACKGROUND

  • Than MP, Pickering JW, Aldous SJ, Cullen L, Frampton CM, Peacock WF, Jaffe AS, Goodacre SW, Richards AM, Ardagh MW, Deely JM, Florkowski CM, George P, Hamilton GJ, Jardine DL, Troughton RW, van Wyk P, Young JM, Bannister L, Lord SJ. Effectiveness of EDACS Versus ADAPT Accelerated Diagnostic Pathways for Chest Pain: A Pragmatic Randomized Controlled Trial Embedded Within Practice. Ann Emerg Med. 2016 Jul;68(1):93-102.e1. doi: 10.1016/j.annemergmed.2016.01.001.

    PMID: 26947800BACKGROUND

  • Flaws D, Than M, Scheuermeyer FX, Christenson J, Boychuk B, Greenslade JH, Aldous S, Hammett CJ, Parsonage WA, Deely JM, Pickering JW, Cullen L. External validation of the emergency department assessment of chest pain score accelerated diagnostic pathway (EDACS-ADP). Emerg Med J. 2016 Sep;33(9):618-25. doi: 10.1136/emermed-2015-205028. Epub 2016 Jul 12.

    PMID: 27406833BACKGROUND

Central Study Contacts

Arwa S. Abdelaziz, resident

CONTACT

+201156748809arwasalah.ed@gmail.com

Alaa M. Ahmed, professor

CONTACT

00201223591937alaa.atya@med.au.edu.eg

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
resident

Study Record Dates

First Submitted

December 14, 2021

First Posted

January 3, 2022

Study Start

December 1, 2022

Primary Completion

January 1, 2024

Study Completion

June 1, 2025

Last Updated

August 2, 2022

Record last verified: 2022-07