Precariousness and Sexual Vulnerability of People From Haiti Living With or Without HIV in French Guiana

NCT05174234 | Completed

• 1 other identifier: Parcours d'Haïti
• Study Type: observational
• Target: 2,189
• Locations: 1 country
• Sites: 1

Brief Summary

French Guiana, a French territory located in South America, faces several social challenges including financial insecurity, unemployment and significant immigration. The degraded living conditions of migrants arriving in the territory are likely to put them in a situation of sexual vulnerability that could increase their risk of acquiring HIV (human immunodeficiency virus). This study proposes to conduct a survey of a group of people living with HIV in French Guiana who were born in Haiti and a group of Haitian people who are not HIV positive. With the help of interviewers who speak Haitian Creole, it will allow us to better understand the life paths of people from Haiti and their periods of vulnerability. Investigators will also focus on the use of testing and retention in care for those living with HIV. The results of this work will allow for the mobilization of resources and better adjustment of social support, prevention and care interventions implemented in French Guiana for migrant populations and/or those in precarious situations.

Conditions

HIV Seropositivity

Keywords

hiv; haiti; french guiana; sexual health

Outcome Measures

Primary Outcomes (1)

• Frequency of unsafe sex

  Frequency of unsafe sex (including forced and paid sex) after arrival in French Guiana of people from Haiti and its association with their living conditions and acquisition of HIV infection

  at inclusion

Secondary Outcomes (17)

• the number of countries of residence

  at inclusion

• level of precariousness

  at inclusion

• level of precariousness

  at inclusion

• level of precariousness - right to stay

  at inclusion

• level of precariousness - health coverage

  at inclusion

Study Arms (3)

People living with HIV

a group of PLWHIV (n=400): women and men aged 18 to 60 years old from Haiti followed at the Cayenne Hospital, the Kourou Hospital or the West Guyanese Hospital (Saint Laurent du Maroni)

People not living with HIV

a group of immigrants from Haiti not known to be infected with HIV (n=1600): women and men aged 18 to 60 years from Haiti

People living with HBV

a group of PLWHBV (n=400): women and men aged 18 to 60 years old from Haiti followed at the Cayenne Hospital, the Kourou Hospital or the West Guyanese Hospital (Saint Laurent du Maroni)

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

A group of PLWHIV and a group of people from Haïti not living with HIV

You may qualify if:

• For the 3 groups, patient :
• Born in Haiti, regardless of current nationality and date of arrival in France
• Aged between 18 and 60 years' old
• Arrived in French Guiana for more than 3 months
• Not opposed to participating in the study
• For the HIV group
• Living with HIV and diagnosed for more than 3 months, regardless of their status regarding hepatitis B and C
• Be followed by one of the study's partner physicians in the hospitals of Cayenne, Kourou or Saint Laurent du Maroni
• For the HBV group
• Living with HBV and diagnosed for more than 3 months, regardless of their status regarding HIV and hepatitis C
• Be followed by one of the study's partner physicians in the hospitals of Cayenne, Kourou or Saint Laurent du Maroni
• For the non-HIV group
• Declared not to be infected with HIV, regardless of their status with respect to hepatitis B and C
• Being followed by one of the study's partner physicians or being recruited in the public space of one of the cities targeted by the study (Cayenne, Matoury, Rémire-Montjoly, Macouria, Kourou, Montsinery-Tonnegrande, Saint-Laurent-du-Maroni or Mana)

You may not qualify if:

• Unable to answer the interviewer in French or Haitian Creole
• Persons under guardianship or trusteeship

Sponsors & Collaborators

• Centre Hospitalier de Cayenne: lead

Study Sites (1)

Centre Hospitalier de Cayenne

Cayenne, France, 97306, French Guiana

Location

Related Publications (1)

• Alcouffe L, Tareau MA, Brun Rambaud G, Lucarelli A, Boutrou M, Thorey C, Cantalupi G, Kpossou K, Huber F, Rabier S, Rochemont DR, Blaise T, Thomas E, Jean G, Pierre Louis R, Zephirin A, Basurko C, Djossou F, Cisse H, Faurous W, Drouaud Q, Mergeay-Fabre M, Adenis A, Nacher M, Vignier N. Sexual Health Determinants During the Life Course and Migration of Haitian-Origin People in French Guiana: Protocol for the Parcours d'Haiti Biographical and Transdisciplinary Study. JMIR Res Protoc. 2025 Jun 12;14:e63586. doi: 10.2196/63586.

  PMID: 40505127 DERIVED

MeSH Terms

Conditions

HIV Seropositivity; Acquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

HIV Infections; Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Slow Virus Diseases

Study Officials

• Nicolas MD Vignier, PhD

  Centre Hospitalier de Cayenne

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 25, 2021
• First Posted: December 30, 2021
• Study Start: November 4, 2021
• Primary Completion: May 31, 2023
• Study Completion: May 31, 2023
• Last Updated: July 29, 2024

Record last verified: 2024-07

Locations

FR (1)