The Second COVID-19 Wave: Collateral Impact on Patients of Liver Disease

NCT05167305 | Completed

• 1 other identifier: ILBS-COVID-07
• Study Type: observational
• Target: 1,316
• Locations: 1 country
• Sites: 1

Brief Summary

Hospital record of the patients of liver disease admitted from April-May 2021 and April-May 2019 will be reviewed. Patients will be analyzed and compared for the demographic characteristics, severity of liver disease at time of admission and outcome in form of survival or mortality, liver transplantation rates in the two time periods and the subsequent 30 d and 90 day readmission rate. Monitoring and assessment: Hospital records of all patients of liver disease needing admission during the April-May 2019 and 2021, but without active COVID-19 infection, will be reviewed. Patients will be analyzed and compared for the demographic characteristics, severity of liver disease at time of admission and outcome in form of survival or mortality, liver transplantation rates in the two time periods and 30 d and 90 d readmission rate.

Conditions

Liver Diseases

Outcome Measures

Primary Outcomes (1)

• Comparison of in-hospital mortality rate of patients of liver disease admitted in April-May 2021 and April-May 2019.

  Until discharge or death

Secondary Outcomes (3)

• Comparison of 30 days readmission rate of patients of liver disease.

  Day 30

• Comparison of 31 to 90 days readmission rate of patients of liver disease.

  Day 31-90

• Comparison of liver transplantation rates in the two time periods i.e., April-May 2021 and April-May 2019.

  3 months

Study Arms (2)

liver disease without COVID-19 infection-April-May 2019

Other: This is an observational study

liver disease without COVID-19 infection -April- May 2021

Other: This is an observational study

Interventions

This is an observational study OTHER

This is an observational study

liver disease without COVID-19 infection -April- May 2021; liver disease without COVID-19 infection-April-May 2019

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients of liver disease without COVID-19 infection admitted in the time period April- May 2021 and April-May 2019.

You may qualify if:

• Patients of liver disease requiring hospital admission

You may not qualify if:

• Active COVID-19 infection at time of admission or acquiring during hospital stay.

Sponsors & Collaborators

• Institute of Liver and Biliary Sciences, India: lead

Study Sites (1)

Institute of Liver & Biliary Sciences

New Delhi, National Capital Territory of Delhi, 110070, India

Location

MeSH Terms

Conditions

Liver Diseases

Condition Hierarchy (Ancestors)

Digestive System Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 17, 2021
• First Posted: December 22, 2021
• Study Start: December 22, 2021
• Primary Completion: December 31, 2021
• Study Completion: December 31, 2021
• Last Updated: January 4, 2022

Record last verified: 2021-12

Data Sharing

• IPD Sharing: Will not share

Locations

IN (1)