Serum IL 26 as a Marker of Disease Activity in SLE

NCT05161988 | Unknown

• 1 other identifier: SLE IL26
• Study Type: observational
• Target: 52
• Locations: 0 countries
• Sites: N/A

Brief Summary

Assessment of serum Interleukin 26 level in SLE patients and compare it with healthy controls. Association of serum interleukin 26 with SLE activity and severity.

Conditions

SLE

Outcome Measures

Primary Outcomes (1)

• Assessment of serum interleukin-26 level .

  Assessment of serum interleukin-26 level in SLE patients and compare it with the serum interleukin-26 level in healthy

  baseline

Secondary Outcomes (1)

• Association !!

  baseline

Eligibility Criteria

• Age: 15 Years - 80 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Any patients fulfillef the critria o 2012 SLE international collaborating clinics and admition to Assiut University are participate in this study .

You may qualify if:

• Adult SLE Patients who fulfilled the 2012 systemic lupus international collaborating clinics (SLICC) criteria

You may not qualify if:

• Individuals with other autoimmune diseases (rheumatoid arthritis dermatomyositis, scleroderma, mixed connective tissue disease).

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Knappe A, Hor S, Wittmann S, Fickenscher H. Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri. J Virol. 2000 Apr;74(8):3881-7. doi: 10.1128/jvi.74.8.3881-3887.2000.

  PMID: 10729163 BACKGROUND

• Maidhof W, Hilas O. Lupus: an overview of the disease and management options. P T. 2012 Apr;37(4):240-9.

  PMID: 22593636 BACKGROUND

• Manson JJ, Rahman A. Systemic lupus erythematosus. Orphanet J Rare Dis. 2006 Mar 27;1:6. doi: 10.1186/1750-1172-1-6.

  PMID: 16722594 BACKGROUND

• Roberts AL, Rizzolo D. Systemic lupus erythematosus: an update on treat-to-target. JAAPA. 2015 Sep;28(9):22-8. doi: 10.1097/01.JAA.0000470432.76823.93.

  PMID: 26251978 BACKGROUND

Central Study Contacts

Fatma Al-zahraa M. Abdel-bary, resident

CONTACT

0201014363853; Zahraamustafa22@yahoo.com

Sherif H. Jalal, professor

CONTACT

0201222675000; Sherif_h918@hotmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident

Study Record Dates

• First Submitted: December 4, 2021
• First Posted: December 17, 2021
• Study Start: December 10, 2021
• Primary Completion: December 1, 2024
• Study Completion: May 1, 2025
• Last Updated: December 17, 2021

Record last verified: 2021-12