Key Insights

Highlights

Success Rate

82% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

6.0%

3 terminated out of 50 trials

Success Rate

82.4%

-4.2% vs benchmark

Late-Stage Pipeline

6%

3 trials in Phase 3/4

Results Transparency

29%

4 of 14 completed with results

Key Signals

4 with results82% success

Data Visualizations

Phase Distribution

28Total
Not Applicable (7)
Early P 1 (4)
P 1 (9)
P 2 (5)
P 3 (1)
P 4 (2)

Trial Status

Completed14
Recruiting11
Unknown11
Active Not Recruiting4
Not Yet Recruiting4
Terminated3

Trial Success Rate

82.4%

Benchmark: 86.5%

Based on 14 completed trials

Clinical Trials (50)

Showing 20 of 20 trials
NCT03093402Phase 2Completed

JBT-101 in Systemic Lupus Erythematosus (SLE)

NCT05966480Phase 2Active Not RecruitingPrimary

Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus

NCT06613360Phase 1RecruitingPrimary

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

NCT07260877Phase 2Recruiting

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus

NCT06839976Phase 1RecruitingPrimary

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

NCT06548620Early Phase 1WithdrawnPrimary

A Study of RD06-04 in Patients With Active Autoimmune Diseases

NCT06775912Early Phase 1RecruitingPrimary

Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases

NCT07364396Phase 1Not Yet Recruiting

Efficacy and Safety of CRC01 in Participants With Severe, Refractory Systemic Lupus Erythematosus

NCT07148115Recruiting

Pregnancies Before the Diagnosis of Systemic Lupus Erythematosus

NCT01761422Active Not RecruitingPrimary

Myocardial Inflammation in Systemic Lupus Erythematosus

NCT06182969Phase 1RecruitingPrimary

A Study of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus.

NCT06265220Phase 1Active Not Recruiting

AB-101 in Combination With B-Cell Depleting mAb in Patients Who Failed Treatment for Class III or IV Lupus Nephritis or Other Forms of Refractory Systemic Lupus Erythematosus

NCT07107659Early Phase 1Recruiting

Safety and Efficacy of ONT01 in Lupus

NCT07203404Early Phase 1RecruitingPrimary

A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases.

NCT06737380Phase 1RecruitingPrimary

UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients

NCT07149402Not Yet RecruitingPrimary

Association of Serum Interleukin-33 Levels With Clinical Manifestations in Systemic Lupus Erythematosus

NCT07069348CompletedPrimary

SLE Severity Linked to Vitamin D Via Treg Cells in Pediatric Patients

NCT05748925Phase 4CompletedPrimary

Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients

NCT05822219Not ApplicableActive Not Recruiting

Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases

NCT03144063Completed

Improving the Assessment of SLE Disease Activity

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