NCT05160883

Brief Summary

This study aim to investigate the neuroimaging changes of hereditary ataxia patients, especially in the SCA3 patients in preclinical or mild stage.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2021

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 30, 2021

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

December 6, 2021

Completed
10 days until next milestone

First Posted

Study publicly available on registry

December 16, 2021

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 25, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 25, 2025

Completed
Last Updated

December 16, 2021

Status Verified

November 1, 2021

Enrollment Period

4.5 years

First QC Date

December 6, 2021

Last Update Submit

December 6, 2021

Conditions

Hereditary Ataxia

Outcome Measures

Primary Outcomes (1)

  • neuroimaging information

    neuroimaging information approached by MRI, including 3D-T1, T2, DTI, rsfMRI, SWI, ASL were collected

    from 2021 to 2025

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients with hereditary ataxia

You may qualify if:

  • genetically diagnosed as Spinocerebellar ataxia

You may not qualify if:

  • deny to follow-up

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Second Affiliated Hospital,Zhejiang University School of Medicine

Hangzhou, Zhejiang, 310009, China

RECRUITING

MeSH Terms

Conditions

Spinocerebellar Degenerations

Condition Hierarchy (Ancestors)

Cerebellar DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesSpinal Cord DiseasesHeredodegenerative Disorders, Nervous SystemNeurodegenerative DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 6, 2021

First Posted

December 16, 2021

Study Start

June 30, 2021

Primary Completion

December 25, 2025

Study Completion

December 25, 2025

Last Updated

December 16, 2021

Record last verified: 2021-11

Locations

CN(1)