Functional Trunk Training in Ataxia Patients

NCT04740359 | Completed DMC

• 1 other identifier: 2020/107
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The study is to examine the effect of functional trunk training on trunk control and upper extremity functions in patients with autosomal recessive ataxia.

Conditions

Ataxia, Spinocerebellar; Ataxias, Hereditary

Keywords

ataxia,rehabilitation,trunk,disabilities

Outcome Measures

Primary Outcomes (4)

• The Functional Independence

  The Functional Independence Scale for Children (WeeFIM) was used determine to independence level.

  through of te study, average 8 weeks

• Trunk impairment

  The Trunk Disorder Scale (TIS) was used to assess static and dynamic sitting balance and trunk coordination

  through of te study, average 8 weeks

• The severity of ataxia

  The International Ataxia Rating Scale (ICARS) was used to determine the severity

  through of te study, average 8 weeks

• The quality of life

  The Children's Quality of Life Scale (PedsQL) was used determine to quality of life level.

  through of te study, average 8 weeks

Secondary Outcomes (2)

• Upper extremity functional performance

  through of te study, average 8 weeks

• Functional Reach Test

  through of te study, average 8 weeks

Study Arms (2)

Control

ACTIVE COMPARATOR

Routine training; mat exercises and perturbation training

Other: Routine training

Study

EXPERIMENTAL

Trunk training; Functional training, mat exercises and perturbation training

Other: Functional training

Interventions

Functional training OTHER

The therapy program was planned for 8 weeks and the sessions were performed in 45 minutes (min) for 3 days a week. The functional reach (forward-lateral-cross), trunk rotation exercises were performed in the sitting positions.(25min) Facilitation of trunk extension and elongation in the prone position (10 min). Thoracic mobilization on exercise ball (10min).

Study

Routine training OTHER

The therapy program was planned for 8 weeks and the sessions were performed in 45 minutes (min) for 3 days a week. The strengthening exercises were applied on the mat (3x10 for the first 4 weeks and 3x15 repetition for the last 4 weeks). Eyes open-closed perturbation training was performed for trunk control in sitting and standing positions (10 min.).

Control

Eligibility Criteria

• Age: 5 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Without any communication impairment (seeing, hearing, hearing),
• Have not had surgery for the upper and lower extremities in the last 6 months,
• Between the ages of 5 and 18,
• The mental level determined by the pediatrician is sufficient,

You may not qualify if:

• Patients who want to leave the study at any stage of the study
• Patients who do not attend regular training

Sponsors & Collaborators

• Hasan Kalyoncu University: lead

Study Sites (1)

Hasan kalyoncu üniversitesi

Gaziantep, Eyalet/Yerleşke, 27100, Turkey (Türkiye)

Location

Related Publications (4)

• Freund JE, Stetts DM. Use of trunk stabilization and locomotor training in an adult with cerebellar ataxia: a single system design. Physiother Theory Pract. 2010 Oct;26(7):447-58. doi: 10.3109/09593980903532234.

  PMID: 20649489 BACKGROUND

• Van de Warrenburg BP, Bakker M, Kremer BP, Bloem BR, Allum JH. Trunk sway in patients with spinocerebellar ataxia. Mov Disord. 2005 Aug;20(8):1006-13. doi: 10.1002/mds.20486.

  PMID: 15838852 BACKGROUND

• Corben LA, Tai G, Wilson C, Collins V, Churchyard AJ, Delatycki MB. A comparison of three measures of upper limb function in Friedreich ataxia. J Neurol. 2010 Apr;257(4):518-23. doi: 10.1007/s00415-009-5352-7. Epub 2009 Oct 13.

  PMID: 19823893 BACKGROUND

• Freund JE, Stetts DM, Vallabhajosula S. Relationships between trunk performance, gait and postural control in persons with multiple sclerosis. NeuroRehabilitation. 2016 Jun 30;39(2):305-17. doi: 10.3233/NRE-161362.

  PMID: 27372366 BACKGROUND

MeSH Terms

Conditions

Spinocerebellar Ataxias; Spinocerebellar Degenerations; Ataxia

Condition Hierarchy (Ancestors)

Cerebellar Ataxia; Cerebellar Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Spinal Cord Diseases; Heredodegenerative Disorders, Nervous System; Neurodegenerative Diseases; Dyskinesias; Neurologic Manifestations; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Res Asst

Model Details: Participants were divided in two groups. Two groups will get two different intervention.

Study Record Dates

• First Submitted: February 2, 2021
• First Posted: February 5, 2021
• Study Start: February 12, 2021
• Primary Completion: September 12, 2021
• Study Completion: November 1, 2021
• Last Updated: March 2, 2023

Record last verified: 2023-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)