Are There Dietary Factors Affecting the Development of Pancreatitis in Patients With Gallstones?

NCT05142657 | Completed DMC

• 1 other identifier: Pancreatitis diet
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

The most common cause of acute pancreatitis is gallstones. It is known that diet and obesity play a role in the formation of gallstones. It has been reported that the risk of gallstone formation is two times higher in obese individuals with a body mass index (BMI) \>30 than in normal-weight individuals with a BMI between 20-25. The epidemiological literature on the relationship between diet and risk of acute pancreatitis is very limited. In addition, it is often unclear which type (acute, recurrent, or chronic) and subtype (gallstone-related or non-gallstone-related) of acute pancreatitis is studied in studies. Although there are studies in the literature evaluating the relationship between diet and development of gallstones or the development of pancreatitis with diet, studies examining the role of diet in the development of pancreatitis in patients with gallstones are very limited. In this study, we aimed to investigate the dietary differences in patients with gallstones who had pancreatitis and those who did not.

Conditions

Diet Habit; Gall Stone; Pancreatitis

Keywords

meat; egg; fat; protein

Outcome Measures

Primary Outcomes (1)

• energy, cholesterol, protein, fat

  Daily energy, cholesterol, protein, fat intake of the participants

  3 days

Study Arms (2)

Case

Patients who have gallstone pancreatitis

Other: diet survey

Control

Patients who have only gallstone

Other: diet survey

Interventions

diet survey OTHER

Dietary survey applied to all participants

Case; Control

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All the participants have gallstone. In control group participants did not have any pancreatitis history. In case group patients have pancreatitis.

You may qualify if:

• years of age,
• having gallbladder stones

You may not qualify if:

• having any cancer,
• being pregnant,
• having chronic liver or kidney disease,
• icterus,
• developing after ERCP.
• years of age
• any cancer,
• pregnancy,
• chronic liver or kidney disease,
• icterus,
• previous pancreatitis attack

Sponsors & Collaborators

• Istanbul Training and Research Hospital: lead

Study Sites (1)

Istanbul Traininng and Research Hospital

Istanbul, 34371, Turkey (Türkiye)

Location

Related Publications (2)

• Setiawan VW, Pandol SJ, Porcel J, Wei PC, Wilkens LR, Le Marchand L, Pike MC, Monroe KR. Dietary Factors Reduce Risk of Acute Pancreatitis in a Large Multiethnic Cohort. Clin Gastroenterol Hepatol. 2017 Feb;15(2):257-265.e3. doi: 10.1016/j.cgh.2016.08.038. Epub 2016 Sep 5.

  PMID: 27609706 BACKGROUND

• Dugum M, Gougol A, Paragomi P, Gao X, Matta B, Yazici C, Tang G, Greer P, Pothoulakis I, O'Keefe SJD, Whitcomb DC, Yadav D, Papachristou GI. Association of Dietary Habits with Severity of Acute Pancreatitis. Curr Dev Nutr. 2018 Oct 8;2(12):nzy075. doi: 10.1093/cdn/nzy075. eCollection 2018 Dec.

  PMID: 30569031 BACKGROUND

MeSH Terms

Conditions

Feeding Behavior; Gallstones; Pancreatitis; Platelet Glycoprotein IV Deficiency

Interventions

Diet Surveys

Condition Hierarchy (Ancestors)

Behavior, Animal; Behavior; Cholelithiasis; Biliary Tract Diseases; Digestive System Diseases; Cholecystolithiasis; Gallbladder Diseases; Calculi; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Pancreatic Diseases

Intervention Hierarchy (Ancestors)

Nutrition Surveys; Surveys and Questionnaires; Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Epidemiologic Measurements; Public Health; Environment and Public Health

Study Officials

• Ufuk O İdiz, M.D

  Istanbul Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 7 Days
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc. Prof. MD. PhD

Study Record Dates

• First Submitted: November 21, 2021
• First Posted: December 2, 2021
• Study Start: June 1, 2021
• Primary Completion: November 20, 2021
• Study Completion: December 1, 2021
• Last Updated: April 14, 2022

Record last verified: 2021-11

Locations

TU (1)