RISK FACTORS OF GALL BLADDER STONE
1 other identifier
observational
166
1 country
1
Brief Summary
Gallbladder disease is a significant health burden in the developed world and its prevalence has risen by more than 20% in the past three decades In the United States, 20-25 million individuals are affected by gallbladder disease, resulting in an average annual treatment cost of $6.2 billion Obesity, diet, rapid weight loss, metabolic syndrome, and conditions such as cirrhosis, Crohn's disease, irritable bowel syndrome, and gallbladder stasis increase the risk of gallstone formation Surgical removal of the gallbladder, cholecystectomy, is the most recommended treatment for gallbladder disease; however, the procedure increases the risk of non-alcoholic fatty liver disease, cirrhosis and metabolic effects
Trial Health
Trial Health Score
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participants targeted
Target at P50-P75 for all trials
Started Apr 2021
1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 12, 2021
CompletedFirst Posted
Study publicly available on registry
March 30, 2021
CompletedStudy Start
First participant enrolled
April 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2022
CompletedMay 26, 2022
March 1, 2021
1 year
March 12, 2021
May 20, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The aim of this study is to unravel the mechanisms responsible for the increased risk of gall stone disease.
All patients will be subjected to:- Complete history taking: With stress on:- * Age sex ( female or male ) comorbid condition (diabetes or hypersensitive). * History of taking lipid lowering drugs. Thorough clinical examination: General examination vital sign ( pulse / blood pressure) height ( centimetre) weight ( kilogram ) body mass index( kg / m2) . Abdominal examination ( organomegly / percussion ). Laboratory Investigation: 1. Lipid profile (total cholesterol, triglyceride, HDL, LDL, VLDL( 2. Abdominal ultrasound. 3. Thyroid function test.(T3 / T4) 4. Estrogen. 5. Random blood suger
15 weeks
Eligibility Criteria
The study will include all adult patients with gallstones admitted to Tropical Medicine Department, Sohage University Hospital.
You may qualify if:
- Adult patients who have gall bladder stone(s)
You may not qualify if:
- Child -
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Sohag Universitylead
Study Sites (1)
at the department of tropical medicine and gastroenterology at sohag University Hospital.
Sohag, Egypt
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident in Tropical Medicine and Gastroenterology Department
Study Record Dates
First Submitted
March 12, 2021
First Posted
March 30, 2021
Study Start
April 1, 2021
Primary Completion
April 1, 2022
Study Completion
May 1, 2022
Last Updated
May 26, 2022
Record last verified: 2021-03