Lipase Levels and Coronavirus Disease 2019

NCT05601258 | Completed

• 1 other identifier: UsakUCevdet3
• Study Type: observational
• Target: 4,000
• Locations: 1 country
• Sites: 1

Brief Summary

Although COVID-19 disease due to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract, heart and coagulation system, symptoms of gastrointestinal system involvement such as abdominal pain, nausea, vomiting and diarrhea are also common. In this study, it was aimed retrospective analysis of clinical and laboratory data of patients who developed pancreatic injury and acute pancreatitis in the course of COVID 19 disease.

Conditions

Pancreatitis; Lipase Increased

Outcome Measures

Primary Outcomes (2)

• The frequency of lipase enzyme elevation will be compared

  From 31th March 2020 until 9th July 2021

• The mortaliy rate will be compared

  From 31th March 2020 until 9th July 2021

Study Arms (2)

patients with higher lipase level

patients with higher lipase levels (higher than the laboratory upper limits) in the course of SARS-CoV-2 infection

Other: Age, gender, hospitalization and mortality rates will be compared

Control

patients with normal lipase levels in the course of SARS-CoV-2 infection

Other: Age, gender, hospitalization and mortality rates will be compared

Interventions

Age, gender, hospitalization and mortality rates will be compared OTHER

Age, gender, hospitalization and mortality rates will be compared

Control; patients with higher lipase level

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Eighteen years of age or older, whose lipase level is measured in the course of COVID 19, will be included in the study.

You may qualify if:

• Patients with lipase levels measured during COVID-19

You may not qualify if:

• Patients with age \<18 years Patients with pregnancy Patients whose lipase levels were not measured in the course of COVID-19 Patients with known solid organ malignacy Patients with known hematologic malignacy

Sponsors & Collaborators

• Uşak University: lead

Study Sites (1)

Cevdet Duran

Uşak, 64200, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pancreatitis

Interventions

Aging; Sex; Hospitalization

Condition Hierarchy (Ancestors)

Pancreatic Diseases; Digestive System Diseases

Intervention Hierarchy (Ancestors)

Growth and Development; Physiological Phenomena; Reproductive Physiological Phenomena; Reproductive and Urinary Physiological Phenomena; Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Cevdet Duran

Study Record Dates

• First Submitted: October 26, 2022
• First Posted: November 1, 2022
• Study Start: March 31, 2020
• Primary Completion: July 9, 2021
• Study Completion: July 9, 2021
• Last Updated: November 1, 2022

Record last verified: 2022-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)