Hemodynamic Changes of Tracheal Intubation With McCoy and Macintosh Laryngoscopes

NCT05133375 | Completed

• 1 other identifier: 11112021
• Study Type: interventional
• Target: 272
• Locations: 1 country
• Sites: 1

Brief Summary

A total of 272 patients were randomly allocated into two groups, Patients in group A were treated with Macintosh laryngoscope and in groups B with McCoy laryngoscope was used for endotracheal intubation. Pulse and systolic blood pressure was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3minutes after intubation. All this information was recorded on a Pro forma.

Conditions

Hemodynamic Rebound

Outcome Measures

Primary Outcomes (2)

• Effect on the pulse of intubation with Macintosh and McCoy laryngoscope

  To measure hemodynamic changes (i.e. pulse) of intubation with Macintosh and McCoy laryngoscope

  After Laryngoscopy, pulse was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3 minutes after intubation.

• Effect on the systolic blood pressure of intubation with Macintosh and McCoy laryngoscope

  To measure hemodynamic changes (i.e. systolic blood pressure) of intubation with Macintosh and McCoy

  After Laryngoscopy, systolic blood pressure was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3 minutes after intubation

Study Arms (2)

GROUP A

EXPERIMENTAL

Macintosh laryngoscope was used for endotracheal intubation.

Procedure: Tracheal Intubation

GROUP B

EXPERIMENTAL

McCoy laryngoscope was used for endotracheal intubation.

Procedure: Tracheal Intubation

Interventions

Tracheal Intubation PROCEDURE

Before reporting to Operation theatre, a detailed pre anesthesia assessment was done in all patients, all necessary laboratory investigations were collected. On OT table pulse and systolic blood pressure was checked by non-invasive method. 18G cannula was passed and ECG was attached. A pillow was placed under the head to obtain classical sniffing position for intubation. All the patients were pre medicated with injection midazolam 0.08mg/kg, injection nalbuphine 0.1 mg/kg, injection dexamethasone 0.08mg/kg and injection metoclopramide 0.1 mg/kg. Pre oxygenation was done with 100% oxygen for 3 mins. Induction was done with injection propofol2 mg/kg, muscle relaxation achieved with injection atracurium 0.5mg/kg. Laryngoscopy was started after 3 minutes by a qualified anesthetist. Pulse and systolic blood pressure was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3 minutes after intubation.

GROUP A; GROUP B

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Both Male and Female
• Age between 18 to 70
• ASA I and II males and females.
• Malampatti I and II.
• Hemodynamically stable, no known ischemic heart disease and no history of hypertension.
• Nil per oral for at least 6 hours.

You may not qualify if:

• Non consenting patient.
• ASA III, IV or V patient.
• Malampati III or IV.
• Cervical instability
• Thyromental distance of less than 6cm, inter incisor distance of less than 3cm.
• Known case of hypertension and ischemic heart disease.
• Pregnant female.
• Body mass index of more than 30.
• Patients of oropharyngeal surgery.
• Unable to Intubate in less than 1 minute.

Sponsors & Collaborators

• CMH Jhelum: lead

Study Sites (1)

CMH

Jhelum, Punjab Province, 49600, Pakistan

Location

MeSH Terms

Interventions

Intubation, Intratracheal

Intervention Hierarchy (Ancestors)

Airway Management; Therapeutics; Intubation; Investigative Techniques

Study Officials

• Muhammad Awais Qarni

  Anesthesiologist

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anesthesiologist

Study Record Dates

• First Submitted: November 11, 2021
• First Posted: November 24, 2021
• Study Start: April 1, 2021
• Primary Completion: October 1, 2021
• Study Completion: October 1, 2021
• Last Updated: November 24, 2021

Record last verified: 2021-11

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)