Regional Anaesthesia in Intensive Care Unit

NCT05131633 | Completed

• 1 other identifier: WEEK'ALR
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 19

Brief Summary

Pain is a major problem in Intensive Care Unit (ICU). Adequate pain management not only means decreasing the pain intensity, but also improving the functionality and allowing the early mobilization that is a prerequisite for improving recovery and decreasing the risk of complications in ICU. The complex problems involved in pain, analgesic interventions, and outcome have been emphasized in several surveys over the past decades, but apparently with only small improvements, despite the existence of several guidelines for perioperative pain management. Regional analgesia techniques (peripheral and neuraxial nerve blocks) have the potential to decrease the physiological stress response to trauma or surgery, reducing the possibility of surgical complications and improving the outcomes. Recent studies suggested that surgical and trauma ICU patients receive opioid-hypnotics continuous infusions to prevent pain and agitation that could increase the risk of posttraumatic stress disorder and chronic neuropathic pain symptoms, and chronic opioid use. Also they may reduce the total amount of opioid analgesics necessary to achieve adequate pain control and the development of potentially dangerous side effects. The use of the regional anesthesia technique in the ICU, however, can, in part, be limited by the presence of hemodynamic instability, bleeding diathesis, and by the fear of the performing procedures potentially associated with significant side effects in heavily sedated patients. Although regional anesthesia emerges as a new and very interesting player for pain management in ICU, today very few data exists about the use of RA (including PNB and neuraxial nerves blocks) by the practicians in ICU/stepdown units. The main objective of this study is to assess the use of RA for pain management both initiates in the operative room for surgical patients then transferred in ICU/stepdown units and performs directly by the practicians in ICU/stepdown units, in several french units.

Conditions

Intensive Care Unit

Keywords

regional anesthesia; intensive care unit; analgesia; pain management

Outcome Measures

Primary Outcomes (1)

• Our primary objective is to assess the global use of RA in ICU/stepdown units

  . Number (prevalence) of RA performed in ICU over 1 week.

  During 1 week of the study

Secondary Outcomes (22)

• assess the use, in ICU/stepdown units patients, of RA previously initiated in the operative room by an anesthesiologist

  During 1 week of the study

• Type of RA

  During 1 week of the study

• Location of RA

  During 1 week of the study

• Who perform RA

  During 1 week of the study

• Name of local anesthetics used

  During 1 week of the study

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All medical, surgical, and trauma patients hospitalized in the participating centers and receiving RA during the one-week study period.

You may qualify if:

• ○ All medical, surgical, and trauma patients hospitalized in the participating centers and receiving RA during the one-week study period.

You may not qualify if:

• Opposition to the processing of personal data
• Age \<18 years old
• Absolute contraindications to the perform RA
• Previous hypersensitivity or anaphylactic reaction to local anesthetics
• Patient under a tutelage measure or placed under judicial protection

Sponsors & Collaborators

• University Hospital, Clermont-Ferrand: lead
• Hôpital Edouard Herriot: collaborator
• Rangueil Hospital: collaborator
• Hospices Civils de Lyon: collaborator
• Hopital Louis Pradel: collaborator
• Hôpital Saint Camille: collaborator
• Hôpital de la Timone: collaborator
• University Hospital, Grenoble: collaborator
• University Hospital, Lille: collaborator
• Saint Antoine University Hospital: collaborator
• University Hospital, Strasbourg: collaborator
• University Hospital, Marseille: collaborator
• Centre Hospitalier Universitaire de Nīmes: collaborator
• CH Aix: collaborator
• CH Martigues: collaborator
• CH Alberville: collaborator
• CH Chambery: collaborator
• Rennes University Hospital: collaborator
• Bichat Hospital: collaborator

Study Sites (19)

CH

Aix-en-Provence, France

Location

CH

Bry-sur-Marne, France

Location

CH

Chambéry, France

Location

CHU

Clermont-Ferrand, 63000, France

Location

Centre Jean-Perrin

Clermont-Ferrand, France

Location

CHU

Grenoble, France

Location

CHU

Lille, France

Location

HCL Centre des Grands Brulés

Lyon, France

Location

HCL Hôpital Sud

Lyon, France

Location

APHM la Timone

Marseille, France

Location

APHM Nord

Marseille, France

Location

CHU

Nîmes, France

Location

AHPH Saint-Antoine

Paris, France

Location

APHP Bichat

Paris, France

Location

CHU

Reims, France

Location

CHU

Rennes, France

Location

CH

Saint-Grégoire, France

Location

CHU

Strasbourg, France

Location

CHU

Toulouse, France

Location

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Raïko Blondonnet

  rblondonnet@chu-clermontferrand.fr

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr

Study Record Dates

• First Submitted: October 3, 2021
• First Posted: November 23, 2021
• Study Start: October 18, 2021
• Primary Completion: November 20, 2021
• Study Completion: December 31, 2021
• Last Updated: February 17, 2023

Record last verified: 2023-02

Locations

FR (19)