Practice of Sedation and Analgesia in Patients With Severe Brain Injury in China

NCT03975751 | Completed DMC

• 1 other identifier: KY2017-062-02
• Study Type: observational
• Target: 387
• Locations: 1 country
• Sites: 1

Brief Summary

Sedation and analgesia is necessary management for patients in the intensive care units. The high-level studies of sedation and analgesia in China are still deficient, especially in patients with brain injuries who even have been excluded from the relevant studies.

Conditions

Intensive Care Unit

Keywords

severe brain injuries; sedation and analgesia; intensive care unit; survey

Outcome Measures

Primary Outcomes (2)

• Performance of sedation assessment

  The percentage of patients receiving sedation assessment

  The previous 24 hours prior to the on-site investigation

• Performance of pain assessment

  The percentage of patients receiving pain assessment

  The previous 24 hours prior to the on-site investigation

Secondary Outcomes (4)

• Use of sedatives

  The previous 24 hours prior to the on-site investigation

• Use of analgesics

  The previous 24 hours prior to the on-site investigation

• ICU mortality

  Within 60 days after on-site investigation

• Hospital mortality

  Within 60 days after on-site investigation

Interventions

The Glasgow Coma Scale (GCS) DIAGNOSTIC_TEST

Use the common GCS, RASS and self-reported pain assessment for evaluating consciousness, agitation/sedation and analgesia.

Also known as: The Richmond Agitation-Sedation Scale (RASS), The self-reported pain assessment

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All the patients at 9am on the on-site investigation day in the participating ICUs will be screened and enrolled according to the inclusion and exclusion criteria.

You may qualify if:

• All adult patients admitted to the participating ICUs on the investigation day

You may not qualify if:

• Age under 18 years
• Less than 24 hours of ICU stay before screening
• Taking part in other studies

Sponsors & Collaborators

• Capital Medical University: lead

Study Sites (1)

ICU, Beijing Tiantan Hospital, Capital Medical University

Beijing, Beijing Municipality, 100050, China

Location

Related Publications (1)

• Chen K, Yang YL, Li HL, Xiao D, Wang Y, Zhang L, Zhou JX. A gap existed between physicians' perceptions and performance of pain, agitation-sedation and delirium assessments in Chinese intensive care units. BMC Anesthesiol. 2021 Feb 25;21(1):61. doi: 10.1186/s12871-021-01286-w.

  PMID: 33627067 DERIVED

MeSH Terms

Conditions

Brain Injuries; Agnosia

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Craniocerebral Trauma; Trauma, Nervous System; Wounds and Injuries; Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Jian-Xin Zhou, MD

  Beijing Tiantan Hospital

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: June 2, 2019
• First Posted: June 5, 2019
• Study Start: January 8, 2019
• Primary Completion: January 8, 2019
• Study Completion: March 9, 2019
• Last Updated: June 5, 2019

Record last verified: 2019-06

Locations

CN (1)