NCT05127707

Brief Summary

The aim of this study was to evaluate the effects of exposure to stigma reduction message frames communicated by visual campaigns and narrative vignettes among a national sample of health professionals.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,842

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 13, 2020

Completed
17 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2020

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

October 28, 2021

Completed
22 days until next milestone

First Posted

Study publicly available on registry

November 19, 2021

Completed
Last Updated

November 19, 2021

Status Verified

November 1, 2021

Enrollment Period

17 days

First QC Date

October 28, 2021

Last Update Submit

November 8, 2021

Conditions

Outcome Measures

Primary Outcomes (6)

  • Rating of willingness to have person with opioid use disorder marry into their family

    Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 5 indicating greater unwillingness and 1 indicating greater willingness to have a person with opioid use disorder marry into the family. Measured via survey questionnaire.

    Measured immediately post-exposure to message frame intervention

  • Rating of willingness to have person with opioid use disorder as a neighbor

    Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 5 indicating greater unwillingness and 1 indicating greater willingness to have a person with opioid use disorder as a neighbor. Measured via survey questionnaire.

    Measured immediately post-exposure to message frame intervention

  • Rating of agreement that opioid use disorder is a medical condition

    Rating of agreement with statement "Opioid use disorder is a chronic medical condition like diabetes mellitus" on 5-point Likert scale with 5 indicating strong disagreement and 1 indicating strong agreement. Measured via survey questionnaire.

    Measured immediately post-exposure to message frame intervention

  • Rating of agreement that individuals with opioid use disorder are to blame

    Rating of agreement with statement "Individuals with opioid use disorder only have themselves to blame for their problem" on 5-point Likert scale with 5 indicating strong disagreement and 1 indicating strong agreement. Measured via survey questionnaire.

    Measured immediately post-exposure to message frame intervention

  • Rating of support for increasing government spending on opioid use disorder treatment

    Rating of support for increasing government spending on treatment of opioid use disorder with 5 indicating strongly favoring and 1 indicating strongly opposing. Measured via survey questionnaire.

    Measured immediately post-exposure to message frame intervention

  • Feeling thermometer measure of warmth toward people with opioid use disorder

    Rating of warmth felt toward people with opioid use disorder with 0 indicating extremely cold and 100 indicating extremely warm. Measured via survey questionnaire.

    Measured immediately post-exposure to message frame intervention

Secondary Outcomes (17)

  • Stigmatizing Language - Addict

    Measured immediately post-exposure to message frame intervention

  • Stigmatizing Language - Substance abuse

    Measured immediately post-exposure to message frame intervention

  • Stigmatizing Language - dirty

    Measured immediately post-exposure to message frame intervention

  • Stigmatizing Language - clean

    Measured immediately post-exposure to message frame intervention

  • Stigmatizing Language - addicted baby

    Measured immediately post-exposure to message frame intervention

  • +12 more secondary outcomes

Study Arms (9)

No exposure control group

NO INTERVENTION

This group was not exposed to any message frame.

Words Matter - Visual Campaign

EXPERIMENTAL

Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings.

Behavioral: Words Matter - Visual Campaign

Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder)

EXPERIMENTAL

Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings and a narrative vignette told from the perspective of a person with opioid use disorder.

Behavioral: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder) Experimental: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)

Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)

EXPERIMENTAL

Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings and a narrative vignette told from the perspective of a clinician.

Behavioral: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)

Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)

EXPERIMENTAL

Participants randomized to this arm were exposed to a visual campaign communicating the importance of use of non-stigmatizing language regarding substance use disorder and opioid use disorder in clinical settings and a narrative vignette told from the perspective of a health system administrator/leader.

Behavioral: Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)

Medication Treatment Works - Visual Campaign

EXPERIMENTAL

Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives.

Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign

Medication Treatment Works - Visual Campaign & Narrative Vignette (Person with OUD)

EXPERIMENTAL

Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives and a narrative vignette told from the perspective of a person with opioid use disorder.

Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder)

Medication Treatment Works - Visual Campaign & Narrative Vignette (Clinician)

EXPERIMENTAL

Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives and a narrative vignette told from the perspective of a clinician.

Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Clinician)

Medication Treatment Works - Visual Campaign & Narrative Vignette (Health System Administrator)

EXPERIMENTAL

Participants randomized to this arm were exposed to a visual campaign communicating the effectiveness of medications for treating opioid use disorder in saving lives and a narrative vignette told from the perspective of a health system administrator/leader.

Behavioral: Medication Treatment for Opioid Use Disorder Works - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)

Interventions

Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings.

Words Matter - Visual Campaign

Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings combined with a narrative vignette told from the perspective of a person with opioid use disorder

Words Matter - Visual Campaign & Narrative Vignette (Messenger: Person with Opioid Use Disorder)

Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings combined with a narrative vignette told from the perspective of a clinician working with patients with opioid use disorder

Words Matter - Visual Campaign & Narrative Vignette (Messenger: Clinician)

Visual campaign emphasizing the importance of using non-stigmatizing language related to substance use and opioid use disorder in clinical settings combined with a narrative vignette told from the perspective of a health system administrator/leader

Words Matter - Visual Campaign & Narrative Vignette (Messenger: Health System Administrator)

Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives

Medication Treatment Works - Visual Campaign

Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives combined with a narrative vignette told from the perspective of a person with opioid use disorder

Medication Treatment Works - Visual Campaign & Narrative Vignette (Person with OUD)

Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives combined with a narrative vignette told from the perspective of a clinician who treats people with opioid use disorder

Medication Treatment Works - Visual Campaign & Narrative Vignette (Clinician)

Visual campaign emphasizing the effectiveness and value of medications to treat opioid use disorder in saving lives combined with a narrative vignette told from the perspective of a health system administrator/leader

Medication Treatment Works - Visual Campaign & Narrative Vignette (Health System Administrator)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • employed as health professional in the United States, including clinicians (e.g., physicians, nurses, physician assistants, pharmacists, and optometrists), technicians and technologists (e.g., laboratory technologist or technician, emergency medical technician, paramedic, licensed practical or licensed vocational nurse, medical records or health information technician, etc.), health aids and assistants (e.g., nursing aide, home health aide, medical assistant, pharmacy aide, phlebotomist, etc.)
  • participant in existing web-based survey panel (IPSOS's KnowledgeNetworks panel and partner opt-in panel)

You may not qualify if:

  • not employed in health profession
  • not able to complete experiment and survey in English

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Johns Hopkins Bloomberg School of Public Health

Baltimore, Maryland, 21205, United States

Location

Related Publications (1)

  • Kennedy-Hendricks A, McGinty EE, Summers A, Krenn S, Fingerhood MI, Barry CL. Effect of Exposure to Visual Campaigns and Narrative Vignettes on Addiction Stigma Among Health Care Professionals: A Randomized Clinical Trial. JAMA Netw Open. 2022 Feb 1;5(2):e2146971. doi: 10.1001/jamanetworkopen.2021.46971.

MeSH Terms

Conditions

Opioid-Related DisordersSubstance-Related DisordersSocial Stigma

Condition Hierarchy (Ancestors)

Narcotic-Related DisordersChemically-Induced DisordersMental DisordersSocial BehaviorBehavior

Study Officials

  • Alene Kennedy-Hendricks, PhD

    Johns Hopkins Bloomberg School of Public Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 28, 2021

First Posted

November 19, 2021

Study Start

November 13, 2020

Primary Completion

November 30, 2020

Study Completion

November 30, 2020

Last Updated

November 19, 2021

Record last verified: 2021-11

Data Sharing

IPD Sharing
Will not share

Locations