NCT06743178

Brief Summary

The aim of this study was to evaluate the effects of exposure to drug-related photos used by the media on emotions, stigma towards people who use drugs, and public health services for this population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,570

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 20, 2024

Completed
19 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 8, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 8, 2024

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

December 16, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 19, 2024

Completed
Last Updated

December 19, 2024

Status Verified

December 1, 2024

Enrollment Period

19 days

First QC Date

December 16, 2024

Last Update Submit

December 16, 2024

Conditions

Outcome Measures

Primary Outcomes (16)

  • Positive and Negative Affect Scale (Angry)

    Rating of feeling angry at the present moment. Item from the Positive and Negative Affect Scale. Measured on 5-point Likert scale with 1 indicating "not at all" and 5 indicating "extremely" their feeling angry at the present moment.

    Immediately post-exposure to photo intervention

  • Positive and Negative Affect Scale (Sympathy)

    Rating of feeling sympathy at the present moment. Item from the Positive and Negative Affect Scale. Measured on 5-point Likert scale with 1 indicating "not at all" and 5 indicating "extremely" their feeling sympathy at the present moment.

    Immediately post-exposure to photo intervention

  • Positive and Negative Affect Scale (Disgust)

    Rating of feeling disgust at the present moment. Item from the Positive and Negative Affect Scale. Measured on 5-point Likert scale with 1 indicating "not at all" and 5 indicating "extremely" their feeling disgust at the present moment.

    Immediately post-exposure to photo intervention

  • Positive and Negative Affect Scale (Pity)

    Rating of feeling pity at the present moment. Item from the Positive and Negative Affect Scale. Measured on 5-point Likert scale with 1 indicating "not at all" and 5 indicating "extremely" their feeling pity at the present moment.

    Immediately post-exposure to photo intervention

  • Social Distance Scale (Family)

    Rating of willingness to have person with substance use disorder marry into their family. Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 1 indicating greater willingness and 5 indicating greater unwillingness to have a person with a substance use disorder marry into the family.

    Immediately post-exposure to photo intervention

  • Social Distance Scale (Neighbor)

    Rating of willingness to have person with substance use disorder as a neighbor. Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 1 indicating greater willingness and 5 indicating greater unwillingness to have a person with a substance use disorder as a neighbor.

    Immediately post-exposure to photo intervention

  • Social Distance Scale (Work Closely)

    Rating of willingness to have person with substance use disorder work closely with them. Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 1 indicating greater willingness and 5 indicating greater unwillingness to have a person with a substance use disorder work closely with them.

    Immediately post-exposure to photo intervention

  • Social Distance Scale (close friend)

    Rating of willingness to have person with substance use disorder as a close personal friend. Item from the Social Distance Scale that measures one element of stigma (desire for social distance). Measured on 5-point Likert scale with 1 indicating greater willingness and 5 indicating greater unwillingness to have a person with a substance use disorder as a close personal friend.

    Immediately post-exposure to photo intervention

  • Feeling-Thermometer measure of warmth towards people with substance use disorders

    Rating of warmth felt toward people with substance use disorder with 0 indicating extremely cold and 100 indicating extremely warm.

    Immediately post-exposure to photo intervention

  • Rating of agreement that recovery is possible

    Rating of agreement with statement "Recovery from a drug addiction is possible" on a 5-point Likert scale with 1 indicating strongly agree and 5 indicating strongly disagree.

    Immediately post-exposure to photo intervention

  • Rating of willingness to have a drug treatment program in their neighborhood

    Rating of willingness to have a drug treatment program in their neighborhood with 1 indicating greater willingness and 5 indicating greater unwillingness. Measured via survey questionnaire.

    Immediately post-exposure to photo intervention

  • Rating of willingness to have a syringe exchange program in their neighborhood

    Rating of willingness to have a syringe exchange program in their neighborhood with 1 indicating greater willingness and 5 indicating greater unwillingness.

    Immediately post-exposure to photo intervention

  • Rating of willingness to have a safe consumption site in their neighborhood

    Participant's rating of willingness to have a safe consumption site in their neighborhood with 1 indicating greater willingness and 5 indicating greater unwillingness.

    Immediately post-exposure to photo intervention

  • Number of participants having a family member with a substance use disorder

    Personal experience of having a family member with a substance use disorder. Three close-ended response options (Yes, No, Don't know) when asked if the participant has ever had a family member with a substance use disorder.

    Immediately post-exposure to photo intervention

  • Number of participants having a close friend with a substance use disorder

    Personal experience of having a close friend with a substance use disorder. Three close-ended response options (Yes, No, Don't know) when asked if the participant has ever had a close friend with a substance use disorder.

    Immediately post-exposure to photo intervention

  • Number of participants having substance use disorder

    Personal experience of having a substance use disorder. Three close-ended response options (Yes; No; Don't Know) when asked if the participant has ever had a substance use disorder. Measured via survey questionnaire.

    Immediately post-exposure to photo intervention

Study Arms (9)

No exposure control group

NO INTERVENTION

This group was not exposed to any drug-related photo.

Photo of person injecting drugs

EXPERIMENTAL

Participants randomized to this arm were exposed to a photo of a person injecting drugs.

Behavioral: Photo of a person injecting drugs

Photo of Emergency Medical Services (EMS) responding to an overdose (White)

EXPERIMENTAL

Participants randomized to this arm were exposed to a photo of EMS responding to a white person who had overdosed.

Behavioral: Photo of EMS responding to an overdose (White)

Photo of EMS responding to an overdose (Black)

EXPERIMENTAL

Participants randomized to this arm were exposed to a photo of EMS responding to a Black person who had overdosed.

Behavioral: Photo of EMS responding to an overdose (Black)

Photo of a person receiving treatment (Jail)

EXPERIMENTAL

Participants randomized to this arm were exposed to a photo of a person receiving methadone treatment in jail.

Behavioral: Photo of a person receiving treatment (Jail)

Photo of a person receiving treatment (Community)

EXPERIMENTAL

Participants randomized to this arm were exposed to a photo of a person receiving methadone treatment in a community setting.

Behavioral: Photo of a person receiving treatment (Community)

Photo of a person in recovery (White)

EXPERIMENTAL

Participants randomized to this arm were exposed to a photo of a white person in recovery in their workplace.

Behavioral: Photo of a person in recovery (White)

Photo of a person in recovery (Black)

EXPERIMENTAL

Participants randomized to this arm were exposed to a photo of a Black person in recovery in their workplace.

Behavioral: Photo of a person in recovery (Black)

Photo of a family member of an overdose decedent

EXPERIMENTAL

Participants randomized to this arm were exposed to a photo of a person who had lost a family member to an overdose.

Behavioral: Photo of a family member of an overdose decedent

Interventions

Exposed to a photo of a person injecting drugs

Photo of person injecting drugs

Exposed to a photo of EMS responding to an overdose (White)

Photo of Emergency Medical Services (EMS) responding to an overdose (White)

Exposed to a photo of EMS responding to an overdose (Black)

Photo of EMS responding to an overdose (Black)

Exposed to a photo of a person receiving treatment (Jail)

Photo of a person receiving treatment (Jail)

Exposed to a photo of a person receiving treatment (Community)

Photo of a person receiving treatment (Community)

Exposed to a photo of a person in recovery (White)

Photo of a person in recovery (White)

Exposed to a photo of a person in recovery (Black)

Photo of a person in recovery (Black)

Exposed to a photo of a family member of an overdose decedent

Photo of a family member of an overdose decedent

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • participant in existing web-based survey panel (NORC's AmeriSpeak)

You may not qualify if:

  • not able to complete experiment and survey in English

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Johns Hopkins Bloomberg School of Public Health

Baltimore, Maryland, 21205, United States

Location

Related Publications (1)

  • Hom JK, Heley K, Bandara S, Kennedy-Hendricks A. The impact of news photographs on drug-related stigma: A randomized message testing experiment in a National Sample of US Adults. Prev Med. 2025 Jun;195:108293. doi: 10.1016/j.ypmed.2025.108293. Epub 2025 Apr 29.

MeSH Terms

Conditions

Opioid-Related DisordersSubstance-Related DisordersSocial Stigma

Interventions

JailsResidence CharacteristicsSalvage Therapy

Condition Hierarchy (Ancestors)

Narcotic-Related DisordersChemically-Induced DisordersMental DisordersSocial BehaviorBehavior

Intervention Hierarchy (Ancestors)

Correctional FacilitiesNon-Medical Public and Private FacilitiesDemographyPopulation CharacteristicsEpidemiologic MeasurementsPublic HealthEnvironment and Public HealthTherapeutics

Study Officials

  • Alene Kennedy-Hendricks, PhD

    Johns Hopkins Bloomberg School of Public Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 16, 2024

First Posted

December 19, 2024

Study Start

March 20, 2024

Primary Completion

April 8, 2024

Study Completion

April 8, 2024

Last Updated

December 19, 2024

Record last verified: 2024-12

Data Sharing

IPD Sharing
Will not share

Locations