NCT05127343

Brief Summary

The aim of the study is to clinically evaluate the retention and caries formation of hydrophilic fissure sealants among adolescents after one year.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 12, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 19, 2021

Completed
2 months until next milestone

Study Start

First participant enrolled

February 1, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2022

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2023

Completed
Last Updated

November 19, 2021

Status Verified

November 1, 2021

Enrollment Period

5 months

First QC Date

November 12, 2021

Last Update Submit

November 12, 2021

Conditions

Keywords

Pit and fissure sealantRetention rateCaries formationHydrophilic sealant

Outcome Measures

Primary Outcomes (1)

  • Retention rate

    * Full retention (FR): The material is fully present on the occlusal surfaces * Partially lost (PL): The material is present, but as a result of either wear or loss of the material, part of the previously sealed fissure, was exposed. * Totally lost (TL): No trace of the material to be detected on the surface

    Change from baseline at 3, 6, 12 months

Secondary Outcomes (1)

  • Caries formation

    Change from baseline at 3, 6, 12 months

Study Arms (2)

Resin based sealant (Ultraseal XT Hydro)

ACTIVE COMPARATOR
Procedure: Sealing deep pits and fissures

Glass ionomer based sealant (Fugi Triage)

ACTIVE COMPARATOR
Procedure: Sealing deep pits and fissures

Interventions

Application of the pit and fissure sealant

Glass ionomer based sealant (Fugi Triage)Resin based sealant (Ultraseal XT Hydro)

Eligibility Criteria

Age12 Years - 16 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Patients who have existing pits and fissures that are anatomically deep and caries susceptible.
  • Healthy patients with no history of previous systematic diseases that can affect their oral health and sealant application.
  • Cooperative patients who will allow the clinical applications

You may not qualify if:

  • Uncooperative behaviour limiting the use of sealants throughout the procedure.
  • Patients with history of medical diseases, drug therapies or any other serious relevant problem.
  • Patients with well coalesced pits and fissures
  • Patients allergic to sealant material
  • Patients who underwent orthodontic treatment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of dentistry

Cairo, 11331, Egypt

Location

MeSH Terms

Conditions

Van der Woude syndrome

Study Officials

  • Iman I ElSayad, Professor

    Cairo University

    STUDY DIRECTOR
  • Heba Helal

    Cairo University

    STUDY DIRECTOR

Central Study Contacts

Iman I ElSayad, Professor

CONTACT

Heba Helal, Post Phd

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Master's Degree student- Faculty of Dentistry

Study Record Dates

First Submitted

November 12, 2021

First Posted

November 19, 2021

Study Start

February 1, 2022

Primary Completion

July 1, 2022

Study Completion

February 1, 2023

Last Updated

November 19, 2021

Record last verified: 2021-11

Locations