NCT05109299

Brief Summary

Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica', the famous 'Toothbrush Tree' used for centuries. The astringent and anti-bacterial properties of Meswak helps reduce tooth decay , fight plaque and prevent gum diseases. Miswak Herb is a rare, potent, priceless, wonder herb that delivers incredible Dental Care benefits.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 15, 2021

Completed
21 days until next milestone

First Posted

Study publicly available on registry

November 5, 2021

Completed
26 days until next milestone

Study Start

First participant enrolled

December 1, 2021

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2022

Completed
Last Updated

November 5, 2021

Status Verified

October 1, 2021

Enrollment Period

4 months

First QC Date

October 15, 2021

Last Update Submit

October 26, 2021

Conditions

Caries

Keywords

Antibacterial, streptococcus mutans, miswak, fluoride

Outcome Measures

Primary Outcomes (1)

  • streptococcus mutans count

    Counting streptococcus mutans, Measurement: Mitis-Salivarius agar plate, Unit: CFUs/mL

    3 months

Study Arms (2)

Miswak toothpaste

EXPERIMENTAL

Dabur meswak herpal toothpaste

Other: Miswak toothpaste

Fluoride toothpaste

ACTIVE COMPARATOR

Signal fluoride toothpaste, containing 1450 ppm of fluoride

Other: Fluoride toothpaste

Interventions

Miswak toothpasteOTHER

Dabur Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica'

Also known as: Dabur meswak
Miswak toothpaste
Fluoride toothpasteOTHER

1450 ppm fluoride toothpaste

Also known as: Signal toothpaste
Fluoride toothpaste

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • High caries risk patients.
  • At least one carious tooth according to CAT caries risk assessment model.
  • Patient compliance

You may not qualify if:

  • Participant in another trial.
  • Using another antimicrobial agents since one month of sampling.
  • Systemic diseases or concomitant medication affecting salivary flow.
  • Parafunctional habits.
  • Pregnancy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry, Cairo University

Cairo, El Manial, 11553, Egypt

Location

Study Officials

  • Omar O Shaalan, PhD

    Lecturer, Conservative Dentistry Department, Faculty of Dentistry, Cairo University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Omar O Shaalan, PhD

CONTACT

00201122665661omar.shaalan@dentistry.cu.edu.eg

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer, Conservative Dentistry Department, Faculty of Dentistry

Study Record Dates

First Submitted

October 15, 2021

First Posted

November 5, 2021

Study Start

December 1, 2021

Primary Completion

March 30, 2022

Study Completion

April 30, 2022

Last Updated

November 5, 2021

Record last verified: 2021-10

Data Sharing

IPD Sharing
Will not share

Locations

EG(1)