NCT05122832

Brief Summary

This is a cross-sectional study that aims to study the prevalence of risk factors of noncommunicable diseases in people aged 18 to 69 years using the standardized and adopted STEPS questionnaire in the Republic of Kazakhstan.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20,400

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 29, 2021

Completed
24 days until next milestone

Study Start

First participant enrolled

October 23, 2021

Completed
25 days until next milestone

First Posted

Study publicly available on registry

November 17, 2021

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 20, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 20, 2022

Completed
Last Updated

March 14, 2023

Status Verified

March 1, 2023

Enrollment Period

10 months

First QC Date

September 29, 2021

Last Update Submit

March 13, 2023

Conditions

Non-Communicable Chronic Diseases

Outcome Measures

Primary Outcomes (8)

  • tobacco use

    currently smoke tobacco, currently smoke tobacco daily, age started smoking, daily smokers smoking manufactured cigarettes

    1 year

  • alcohol consumption

    lifetime abstainers, past 12 month abstainers, currently drink (drank alcohol in the past 30 days), heavy episodic drinking (6 or more drinks on any occasion in the past 30 days).

    1 year

  • physical activity

    insufficient physical activity (defined as \< 150 minutes of moderate-intensity activity per week, or equivalent), physical activity on average per day (minutes), not engaging in vigorous activity.

    1 year

  • unhealthy diet

    days fruit consumed in a typical week, servings of fruit consumed on average per day, days vegetables consumed in a typical week, servings of vegetables consumed on average per day, less than 5 servings of fruit and/or vegetables on average per day, always or often add salt or salty sauce to their food before eating or as they are eating, always or often eat processed foods high in salt.

    1 year

  • BMI

    overweight (BMI ≥ 25 kg/m2), obese (BMI ≥ 30 kg/m2), normal weight

    1 year

  • raised blood pressure

    systolic blood pressure - SBP (mmHg), including those currently on medication for raised BP, diastolic blood pressure - DBP (mmHg), including those currently on medication for raised BP, raised BP (SBP ≥ 140 and/or DBP ≥ 90 mmHg or currently on medication for raised BP), raised BP (SBP ≥ 140 and/or DBP ≥ 90 mmHg or currently on medication for raised BP) who are not currently on medication for raised BP.

    1 year

  • raised blood glucose

    fasting blood glucose, including those currently on medication for raised blood glucose, impaired fasting glycaemia (plasma venous value ≥6.1 mmol/L (110 mg/dl) and \<7.0 mmol/L (126 mg/dl)), raised fasting blood glucose (plasma venous value ≥ 7.0 mmol/L (126 mg/dl)) or currently on medication for raised blood glucose.

    1 year

  • abnormal blood lipids

    total blood cholesterol, including those currently on medication for raised cholesterol, raised total cholesterol,

    1 year

Study Arms (1)

The study Group

Population of Kazakhstan

Diagnostic Test: Blood testDiagnostic Test: STEPwise Approach to NCD Risk Factor Surveillance (STEPS)Diagnostic Test: Spirometry

Interventions

Blood testDIAGNOSTIC_TEST

Glucose Glycosylated hemoglobin Triglycerides Total cholesterol HDL Cholesterol LDL Cholesterol Creatinine COVID-19 Antibody IgM to N protein SARS-Cov-2 (Abbott) COVID-19 Antibody IgG to N protein SARS-Cov-2 (Abbott)

The study Group
STEPwise Approach to NCD Risk Factor Surveillance (STEPS)DIAGNOSTIC_TEST

The WHO STEPwise Approach to NCD Risk Factor Surveillance (STEPS) is a simple, standardized method for collecting, analysing and disseminating data on key NCD risk factors in countries. The survey instrument covers key behavioral risk factors: tobacco use, alcohol consumption, physical activity, unhealthy diet, as well as key biological risk factors: overweight and obesity, raised blood pressure, raised blood glucose, and abnormal blood lipids. Through the use of expanded modules, the survey instrument can be expanded to cover a range of topics beyond these risk factors, such as oral health, sexual health and road safety.

The study Group
SpirometryDIAGNOSTIC_TEST

Spirometry is a common office test used to assess how well your lungs work by measuring how much air you inhale, how much you exhale and how quickly you exhale.

The study Group

Eligibility Criteria

Age18 Years - 69 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

All ethnic groups in Kazakhstan

You may qualify if:

  • Age Limits 18-69 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kazakhstan

Almaty, 050020, Kazakhstan

Location

Related Publications (2)

  • Baspakova A, Abitova AZ, Mussin NM, Kaliyev AA, Yerimbetova G, Zhumagaliyeva S, Ashimova Z, Zhilisbayeva KR, Umbetova AA, Nurtazina AU, Tamadon A. Sex differentials in the prevalence of behavioral risk factors and non-communicable diseases in adult populations of West Kazakhstan. Front Public Health. 2024 Feb 14;12:1333887. doi: 10.3389/fpubh.2024.1333887. eCollection 2024.

    PMID: 38420037DERIVED

  • Nursultanova L, Kabulbayev K, Ospanova D, Tazhiyeva A, Datkhayev U, Saliev T, Tanabayeva S, Fakhradiyev I. Prevalence of chronic kidney disease in Kazakhstan: evidence from a national cross-sectional study. Sci Rep. 2023 Sep 7;13(1):14710. doi: 10.1038/s41598-023-42031-2.

    PMID: 37679536DERIVED

MeSH Terms

Conditions

Noncommunicable Diseases

Interventions

Hematologic TestsSpirometry

Condition Hierarchy (Ancestors)

Disease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Clinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisInvestigative TechniquesRespiratory Function TestsDiagnostic Techniques, Respiratory System

Study Officials

  • Timur M Saliev

    S.D. Asfendiyarov Kazakh National Medical University

    PRINCIPAL INVESTIGATOR

  • Ildar Fakhradiyev, PhD

    S.D. Asfendiyarov Kazakh National Medical University

    STUDY CHAIR

  • Mukhtar B Kulimbet, MD/MSc

    S.D. Asfendiyarov Kazakh National Medical University

    STUDY DIRECTOR

  • Zhumaly A Kauyzbay, PhD, AP

    Joint Stock Company - South Kazakhstan Medical Academy

    PRINCIPAL INVESTIGATOR

  • Samat S Saparbayev, PhD

    West Kazakhstan Marat Ospanov Medical University

    PRINCIPAL INVESTIGATOR

  • Alma U Nurtazina, MD/PhD

    NCJSC Semey Medical University

    PRINCIPAL INVESTIGATOR

  • Bayan A Ainabekova, MD/DMSc

    NCJSC Astana Medical University

    PRINCIPAL INVESTIGATOR

  • Anar A Turmukhambetova, DMSc

    NCJSC Karaganda Medical University

    PRINCIPAL INVESTIGATOR

  • Maksut K Kulzhanov, DMSc

    Kazakhstan's Medical University "KSPH"

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head of the Laboratory of Experimental Medicine

Study Record Dates

First Submitted

September 29, 2021

First Posted

November 17, 2021

Study Start

October 23, 2021

Primary Completion

August 20, 2022

Study Completion

August 20, 2022

Last Updated

March 14, 2023

Record last verified: 2023-03

Locations

KA(1)