Effect of Proprioceptive Neuromuscular Facilitation on Blood Pressure

NCT05110365 | Completed DMC

• 1 other identifier: REC/01045 Raja Saddam
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

To determine the effect of Proprioceptive Neuromuscular Facilitation exercise on blood pressure in patient with mild to moderate hypertension.Both genders will be included.Patients aged between 40 and 60 years with mild and moderate hypertension.Systolic blood pressure 130-160 mmHg or Diastolic Blood Pressure 80-100 mmHg. Sphygmomanometer and EuroQoL five-dimensional instrument would be used for the 'Pre' \& 'Post' assessment.

Conditions

Hypertension

Keywords

proprioceptive neuromuscular facilitations; ankle brachial index; diabetes

Outcome Measures

Primary Outcomes (1)

• sphygmomanometer

  sphygmomanometer will be used for measuring blood pressure and ankle brachial index

  12 weeks

Secondary Outcomes (1)

• (EuroQoL five-dimensional instrument )

  12 weeks

Study Arms (2)

proprioceptive neuromuscular facilitation

EXPERIMENTAL

proprioceptive neuromuscular facilitation techniques

Other: Proprioceptive Neuromuscular Facilitation

control

NO INTERVENTION

no intervention

Interventions

Proprioceptive Neuromuscular Facilitation OTHER

The patient will be provided with mild to moderate resistance PNF pattern which is a type of Endurance training which decreases BP through a reduction in systemic vascular resistance(15).In a regimen as follow with the frequency of 3 days a week, a repetition of 3 sets for one hour and a total duration of 3 months(16). The PNF patterns will be diagonal 1 (D1) and diagonal 2 (D2) patterns. Both patterns are subdivided into: A) Moving into Flexion: the toes start flexed and ends extended. Ankle and foot start plantar flexed; everted and ends dorsiflexed inverted. Tibia starts externally rotated and ends internally rotated. Knee starts extended, and ends flexed. The hip starts extended, abducted, internally rotated and ends flexed, adducted, externally rotated.B) Moving into Extension: The start and end are reversed to "D1 Moving into Flexion"

proprioceptive neuromuscular facilitation

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Both genders will be included.
• Patients aged between 40 and 60 years with mild and moderate hypertension.
• Systolic blood pressure 130-160 mmHg or Diastolic blood pressure 80-100 mmHg.
• Mild and moderate hypertension with diabetes

You may not qualify if:

• Severe hypertensive patients.
• Patient on smoking
• Patient with severe complications and comorbidities.
• Not willing to give consent/ data

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Valley Medical Complex Abbottabad

Abbottābād, Kpk, Pakistan

Location

Related Publications (9)

• Linke A, Erbs S, Hambrecht R. Effects of exercise training upon endothelial function in patients with cardiovascular disease. Front Biosci. 2008 Jan 1;13:424-32. doi: 10.2741/2689.

  PMID: 17981557 BACKGROUND

• Papaioannou TG, Oikonomou E, Lazaros G, Christoforatou E, Vogiatzi G, Tsalamandris S, Chasikidis C, Kalambogias A, Mavratzas T, Stofa E, Mystakidi VC, Latsios G, Deftereos S, Tousoulis D. Arterial stiffness and subclinical aortic damage of reclassified subjects as stage 1 hypertension according to the new 2017 ACC/AHA blood pressure guidelines. Vasa. 2019 May;48(3):236-243. doi: 10.1024/0301-1526/a000765. Epub 2018 Dec 10.

  PMID: 30526401 BACKGROUND

• Varounis C, Katsi V, Nihoyannopoulos P, Lekakis J, Tousoulis D. Cardiovascular Hypertensive Crisis: Recent Evidence and Review of the Literature. Front Cardiovasc Med. 2017 Jan 10;3:51. doi: 10.3389/fcvm.2016.00051. eCollection 2016.

  PMID: 28119918 BACKGROUND

• Singh S, Shankar R, Singh GP. Prevalence and Associated Risk Factors of Hypertension: A Cross-Sectional Study in Urban Varanasi. Int J Hypertens. 2017;2017:5491838. doi: 10.1155/2017/5491838. Epub 2017 Dec 3.

  PMID: 29348933 BACKGROUND

• Papadopoulos DP, Sanidas EA, Viniou NA, Gennimata V, Chantziara V, Barbetseas I, Makris TK. Cardiovascular hypertensive emergencies. Curr Hypertens Rep. 2015 Feb;17(2):5. doi: 10.1007/s11906-014-0515-z.

  PMID: 25620633 BACKGROUND

• Hindle KB, Whitcomb TJ, Briggs WO, Hong J. Proprioceptive Neuromuscular Facilitation (PNF): Its Mechanisms and Effects on Range of Motion and Muscular Function. J Hum Kinet. 2012 Mar;31:105-13. doi: 10.2478/v10078-012-0011-y. Epub 2012 Apr 3.

  PMID: 23487249 BACKGROUND

• Kim EK, Lee DK, Kim YM. Effects of aquatic PNF lower extremity patterns on balance and ADL of stroke patients. J Phys Ther Sci. 2015 Jan;27(1):213-5. doi: 10.1589/jpts.27.213. Epub 2015 Jan 9.

  PMID: 25642076 BACKGROUND

• Pereira MP. Proprioceptive neuromuscular facilitation does not increase blood pressure of healthy elderly women. Physiother Theory Pract. 2012 Jul;28(5):412-6. doi: 10.3109/09593985.2011.609582. Epub 2011 Oct 18.

  PMID: 22007735 BACKGROUND

• Fagard RH, Cornelissen VA. Effect of exercise on blood pressure control in hypertensive patients. Eur J Cardiovasc Prev Rehabil. 2007 Feb;14(1):12-7. doi: 10.1097/HJR.0b013e3280128bbb.

  PMID: 17301622 BACKGROUND

MeSH Terms

Conditions

Hypertension; Diabetes Mellitus

Interventions

Muscle Stretching Exercises

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• sania aziz, MSNMPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 26, 2021
• First Posted: November 5, 2021
• Study Start: June 26, 2021
• Primary Completion: August 15, 2022
• Study Completion: August 18, 2022
• Last Updated: September 23, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)