Influencing Factors on Gait Variability in PD
Influencing Factors and Improving Strategy on Gait Variability in People With Parkinson's Disease
1 other identifier
observational
100
1 country
1
Brief Summary
The principal motor features of Parkinson's disease (PD) include rigidity, tremor, bradykinesia, and postural instability. These motor deficits might cause gait dysfunction including reduced gait velocity, stride length, arm swing, and increased gait variability. Among these, increase in gait variability increased fall risk and served as a marker of disease progression. Previous studies reported that some factors might influence gait variability. However, which one contributes most has not yet been verified. Therefore, the purpose of the present study is to identify the more related influencing factors on gait variability in people with PD.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Nov 2021
1 active site
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Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 13, 2021
CompletedStudy Start
First participant enrolled
November 1, 2021
CompletedFirst Posted
Study publicly available on registry
November 5, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2022
CompletedNovember 5, 2021
October 1, 2021
1.2 years
October 13, 2021
October 25, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (7)
Gait variability
Using GAITRite system to measure coefficient of variation
10 minutes
Walking speed
Using GAITRite system to evaluate
10 minutes
Sensory organization test
Using NeuroCom Smart Balance Master to measure
20 minutes
Part III of the Unified Parkinson's Disease Rating Scale
The score ranged from 0 to 72. Higher scores show increased severity.
20 minutes
Tinetti Balance Scale
The score ranged from 0 to 28. Higher scores show better balance.
10 minutes
New freezing of gait questionnaire
The score ranged from 0 to 29. Higher scores show increased severity in freezing of gait.
15 minutes
Montreal Cognitive Assessment
The score ranged from 0 to 30. Higher scores show better cognitive function.
20 minutes
Eligibility Criteria
People with Parkinson's disease
You may qualify if:
- Idiopathic PD
- Hoehn and Yahr stages I through III
- Ability to stand and walk 5 m independently with or without any walking aids
- Stable medication usage
You may not qualify if:
- Unstable medical conditions
- Any neurological, cardiopulmonary or orthopedic problem/diseases that may interfere with participating the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University
Taipei, 112, Taiwan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
October 13, 2021
First Posted
November 5, 2021
Study Start
November 1, 2021
Primary Completion
December 31, 2022
Study Completion
December 31, 2022
Last Updated
November 5, 2021
Record last verified: 2021-10