Electrocardiographic and Cardiac Magnetic Resonance Predictors of Ventricular Arrhythmias in Cardiomyopathic Patients

NCT05078125 | Unknown FDA Device

• 1 other identifier: AssiutU KMAly
• Study Type: observational
• Target: 79
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to assess ECG changes for predicting ventricular arrhythmia in cardiomyopathic patients

Conditions

Premature Ventricular Complex

Outcome Measures

Primary Outcomes (1)

• Twenty-four hours Holter monitoring after Magnetic Resonance Imaging

  24 Holter monitoring to detect PVCs burden which is defined as ≥10% of total beats

  One year

Interventions

Holter monitoring DEVICE

24 hours Holter monitoring

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study is anticipated to include all consecutive eligible cardiomyopathic patients.

You may qualify if:

• Patients with ischemic and non-ischemic cardiomyopathy, EF \< 40 %
• Patient haemodynamically stable
• Patients accept to make test

You may not qualify if:

• Patients with underlying arrhythmia ex heart block or atrial arrhythmia like PACs, AF.
• Patients on arrhythmogenic drugs ex digitalis, amiodarone.
• Patients on underlying Pacemaker device or CRT-D.
• Patients with MI in less than 40 days
• Patients refuse to make test .

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Mathew T, Williams L, Navaratnam G, Rana B, Wheeler R, Collins K, Harkness A, Jones R, Knight D, O'Gallagher K, Oxborough D, Ring L, Sandoval J, Stout M, Sharma V, Steeds RP; British Society of Echocardiography Education Committee. Diagnosis and assessment of dilated cardiomyopathy: a guideline protocol from the British Society of Echocardiography. Echo Res Pract. 2017 Jun;4(2):G1-G13. doi: 10.1530/ERP-16-0037.

  PMID: 28592613 RESULT

• Pinto YM, Elliott PM, Arbustini E, Adler Y, Anastasakis A, Bohm M, Duboc D, Gimeno J, de Groote P, Imazio M, Heymans S, Klingel K, Komajda M, Limongelli G, Linhart A, Mogensen J, Moon J, Pieper PG, Seferovic PM, Schueler S, Zamorano JL, Caforio AL, Charron P. Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases. Eur Heart J. 2016 Jun 14;37(23):1850-8. doi: 10.1093/eurheartj/ehv727. Epub 2016 Jan 19.

  PMID: 26792875 RESULT

• Sharma E, Arunachalam K, Di M, Chu A, Maan A. PVCs, PVC-Induced Cardiomyopathy, and the Role of Catheter Ablation. Crit Pathw Cardiol. 2017 Jun;16(2):76-80. doi: 10.1097/HPC.0000000000000106.

  PMID: 28509708 RESULT

• Lee DC, Markl M, Dall'Armellina E, Han Y, Kozerke S, Kuehne T, Nielles-Vallespin S, Messroghli D, Patel A, Schaeffter T, Simonetti O, Valente AM, Weinsaft JW, Wright G, Zimmerman S, Schulz-Menger J. The growth and evolution of cardiovascular magnetic resonance: a 20-year history of the Society for Cardiovascular Magnetic Resonance (SCMR) annual scientific sessions. J Cardiovasc Magn Reson. 2018 Jan 31;20(1):8. doi: 10.1186/s12968-018-0429-z.

  PMID: 29386064 RESULT

MeSH Terms

Conditions

Ventricular Premature Complexes

Interventions

Electrocardiography, Ambulatory

Condition Hierarchy (Ancestors)

Cardiac Complexes, Premature; Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Cardiac Conduction System Disease; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electrocardiography; Heart Function Tests; Diagnostic Techniques, Cardiovascular; Diagnostic Techniques and Procedures; Diagnosis; Electrodiagnosis; Monitoring, Ambulatory; Monitoring, Physiologic

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor of cardiology .Luxor International Hospital

Study Record Dates

• First Submitted: October 2, 2021
• First Posted: October 14, 2021
• Study Start: April 1, 2022
• Primary Completion: December 31, 2022
• Study Completion: March 30, 2023
• Last Updated: January 25, 2022

Record last verified: 2022-01