The Incidence and Predictors of Developing Atrial Fibrillation in Patients With Inferior ST-segment Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention

NCT03854448 | Unknown

• 1 other identifier: AF in inferior STEMI after PCI
• Study Type: observational
• Target: 109
• Locations: 0 countries
• Sites: N/A

Brief Summary

Is to analyze the incidence and predictors of developing AF in patients with inferior infarction who undergo PCI with and without atrial and SN branches occlusion

Conditions

Atrial Fibrillation

Keywords

inferior STEMI

Outcome Measures

Primary Outcomes (1)

• incidence of atrial fibrillation in inferior STEMI patients after primary Percutaneous Coronary Intervention

  incidence of atrial fibrillation in inferior STEMI patients after primary Percutaneous Coronary Intervention

  baseline

Secondary Outcomes (1)

• atrial branches occlusion and left atrial volume index as predictors of atrial fibrillation

  baseline

Interventions

holter monitoring DEVICE

Transthoracic Echocardiography (TTE) Left atrial ( LA) volume will be measured using standard apical two- and four-chamber views on the frame just prior to mitral valve opening and as specified by current American Society of Echocardiography guidelines (10) LA volume is indexed to body surface area. Mitral inflow velocity is obtained in the apical four-chamber view by placing a pulsed-Doppler sample volume between the tips of the mitral leaflets. Mitral annular velocity is assessed during the early phase of diastole(e=) using pulsed-wave Doppler sampling of septal mitral annular motion from the four chamber view. 24 to 48 hours Holter monitoring after 1 month after PCI

Also known as: echocardiography

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients with inferior S-T elevation myocardial infarction

You may qualify if:

• Patients with inferior STEMI who will undergo PPCI (primary percutaneous coronary intervention )

You may not qualify if:

• A history of preexisting AF
• Prior documentation of heart failure or reduced left ventricular ejection fraction \< 50%,
• Severe valvular disease ( rheumatic , sclerotic ) or secondary to AMI
• Left ventricular hypertrophy : enlargement and thickening of the walls of the ventricle
• Patients with inferior STEMI treated with intravenous thrombolysis or conservative strategy
• Patients with inferior STEMI who undergo primary PCI and associated with right ventricular or posterior infarction
• History of pulmonary embolism or COPD ( chronic obstructive pulmonary disease )
• Those with thyrotoxicosis

Sponsors & Collaborators

• Assiut University: lead

Related Links

• Clinical factors associated with the development of atrial fibrillation in the year following STEMI treated by primary PCI
• Impact of atrial fibrillation in patients with ST-elevation myocardial infarction treated with percutaneous coronary intervention
• Acute regional left atrial ischemia causes acceleration of atrial drivers during atrial fibrillation
• Atrial coronary artery occlusion during elective percutaneous coronary angioplasty
• Sinus arrest caused by occlusion of the sinus node artery during percutaneous coronary intervention for lesions of the proximal right coronary artery
• Left Atrial Volume: Important Risk Marker of Incident Atrial Fibrillation
• Coronary artery disease affecting the atrial branches is an independent determinant of atrial fibrillation after myocardial infarction
• Electrophysiological Effects of Selective Atrial Coronary Artery Occlusion in Humans
• Long Term Prognosis of Atrial Fibrillation in ST-Elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention
• Left Atrial Size : Physiologic Determinants and Clinical Applications

MeSH Terms

Conditions

Atrial Fibrillation

Interventions

Electrocardiography, Ambulatory; Echocardiography

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Electrocardiography; Heart Function Tests; Diagnostic Techniques, Cardiovascular; Diagnostic Techniques and Procedures; Diagnosis; Electrodiagnosis; Monitoring, Ambulatory; Monitoring, Physiologic; Cardiac Imaging Techniques; Diagnostic Imaging; Ultrasonography

Study Officials

• Yehia Taha Kishk kishk, MD

  Professor of cardiology department Assiut University

  STUDY CHAIR

• Mohamed Ali Mohamed Tohamy tohamy, MD

  Lecturer of cardiology department Assiut University

  STUDY DIRECTOR

Central Study Contacts

ahmed atef ahmed atef atef

CONTACT

01156930941; ahmed3242166@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: February 24, 2019
• First Posted: February 26, 2019
• Study Start: March 1, 2019
• Primary Completion: August 1, 2019
• Study Completion: September 1, 2019
• Last Updated: February 28, 2019

Record last verified: 2019-02