NCT05074901

Brief Summary

KANOPEE is a free smartphone application providing screening, follow-up tools and autonomous digital interventions to lower psycho-social stress and its repercussions on sleep and behaviors in the general population. Additionally, KANOPEE permits an adaptation of the intervention to the subject (i.e., an adapted waiting period, frequency, and content), enabling to perform innovative trial conditions. The objective of this long-term study is to evaluate the efficacy of KANOPEE on users among the French general population exposed to psycho-social stress.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20,000

participants targeted

Target at P75+ for not_applicable

Timeline
20mo left

Started Apr 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress79%
Apr 2020Dec 2027

Study Start

First participant enrolled

April 22, 2020

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

September 20, 2021

Completed
22 days until next milestone

First Posted

Study publicly available on registry

October 12, 2021

Completed
5.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2026

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2027

Last Updated

October 12, 2021

Status Verified

September 1, 2021

Enrollment Period

6.7 years

First QC Date

September 20, 2021

Last Update Submit

September 29, 2021

Conditions

Keywords

e-healthembodied conversational agentecological momentary assessmentecological momentary intervention

Outcome Measures

Primary Outcomes (3)

  • Sleep complaints

    measured by the Insomnia Severity Index (ISI), total score ranging from 0 to 28, higher score indicating higher sleep complaint.

    weekly, from the downloading of the app until two weeks after the end of the intervention

  • Fatigue complaints

    measured by the Fatigue Severity Scale (FSS), total score ranging from 1 to 7, higher score indicating higher perceived fatigue.

    weekly, from the downloading of the app until two weeks after the end of the intervention

  • Depression and anxiety complaints

    measured by the Patient Health Questionnaire 4 items (PHQ-4), total score ranging from 0 to 12, higher scores indicating higher depression or anxiety complaints.

    weekly, from the downloading of the app until two weeks after the end of the intervention

Secondary Outcomes (8)

  • Total Sleep Time

    daily, from the downloading of the app until two weeks after the end of the intervention

  • Sleep Efficiency

    daily, from the downloading of the app until two weeks after the end of the intervention

  • Time In Bed

    daily, from the downloading of the app until two weeks after the end of the intervention

  • Sleep Onset Latency

    daily, from the downloading of the app until two weeks after the end of the intervention

  • Wakefulness After Sleep Onset

    daily, from the downloading of the app until two weeks after the end of the intervention

  • +3 more secondary outcomes

Other Outcomes (1)

  • application's acceptance

    facultative questionnaire that user can fill up after any interaction with the app (thus weekly)

Study Arms (2)

digital behavioral intervention

EXPERIMENTAL

Digital behavioral interventions to improve mood and decrease fatigue, sleep complaints and substance usage.

Behavioral: digital behavioral intervention

e-diaries

NO INTERVENTION

Ecological momentary assessment based on e-diaries on a weekly basis to evaluate sleep/wake schedules, physical activity, substance usage and nutrition.

Interventions

interaction with a conversational agent to implement physical and cognitive programs

digital behavioral intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Being aged 18 years old and over (the app is available for younger users but their data will not be analyzed)
  • having downloaded the app
  • having a smartphone Android or Iphone
  • being located in France
  • having accepted the electronic informed consent

You may not qualify if:

  • having clicked on the "emergency button" (in the app, there is a warning message : this app is not for emergency situations. If you need an urgent psychological support, click here")
  • having downloaded the app but without answering any questionnaire

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Bordeaux

Bordeaux, 33000, France

RECRUITING

Related Publications (1)

  • Sagaspe P, Sanchez-Ortuno MM, Dupuy L, Pecune F, Coelho J, Micoulaud-Franchi JA, Levavasseur Y, de Sevin E, Chanteclair A, Philip P, Salles N. Perceptions and Effectiveness of a Fully Automated Brief Behavioral Insomnia Therapy, Delivered by a Virtual Companion, in Older and Young Adults. Innov Aging. 2024 Sep 24;9(2):igae086. doi: 10.1093/geroni/igae086. eCollection 2025.

MeSH Terms

Conditions

Mental DisordersStress, PsychologicalSleep Initiation and Maintenance DisordersDepressionAnxiety Disorders

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • Pierre Philip, Pr

    University of Bordeaux

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Etienne de Sevin, Ph.D.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: Open populational trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

September 20, 2021

First Posted

October 12, 2021

Study Start

April 22, 2020

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2027

Last Updated

October 12, 2021

Record last verified: 2021-09

Data Sharing

IPD Sharing
Will not share

Locations