Surgery for Delay-recognized or Defer-operated Type A Aortic Dissection

NCT05044494 | Completed

• 1 other identifier: 21MMHIS005e
• Study Type: observational
• Target: 68
• Locations: 0 countries
• Sites: N/A

Brief Summary

From November 2004 to June 2020, there were more than 200 patients with acute TAAD patients who underwent aortic surgery at our hospital.Of all the patients in the study period, there were 34 patients (defined as study group) who sought for medical attention with symptoms for several days (median 5 days, range 3-7 days) or deferred aortic surgery several days later (median 3 days, range 2-7 days) even though acute TAAD was diagnosed on the same day when chest pain or back pain occurred. For reducing the selection bias, propensity score matching (PSM) was used to match the study group with the control group from all the patients treated at our hospital during the study period. Comparison between the two groups was performed.

Conditions

Aortic Dissection

Outcome Measures

Primary Outcomes (1)

• surgical mortality

  in-hospital death

  2004-2020

Study Arms (2)

study group

non-prompt surgery after acute type a aortic dissection occurred

Procedure: non-prompt surgery

control group

prompt surgery after acute type a aortic dissection occurred

Interventions

non-prompt surgery PROCEDURE

study group

Eligibility Criteria

• Age: 33 Years - 83 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

From November 2004 to June 2020, there were more than 200 consecutive patients with acute TAAD treated surgically at our hospital. Among all the acute TAAD patients, 34 patients sought for medical attention with symptoms (chest pain, back pain or shortness of breath) for several days or deferred aortic surgery several days later although acute TAAD was diagnosed on the same day when chest pain or back pain occurred.

You may qualify if:

• the patients sought for medical attention with symptoms (chest pain, back pain or shortness of breath) for several days or deferred aortic surgery several days later although acute TAAD was diagnosed on the same day when chest pain or back pain occurred

Sponsors & Collaborators

• Mackay Memorial Hospital: lead

MeSH Terms

Conditions

Aortic Dissection

Condition Hierarchy (Ancestors)

Dissection, Blood Vessel; Aneurysm; Vascular Diseases; Cardiovascular Diseases; Acute Aortic Syndrome; Aortic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 12, 2021
• First Posted: September 14, 2021
• Study Start: November 1, 2004
• Primary Completion: June 1, 2020
• Study Completion: June 1, 2020
• Last Updated: September 14, 2021

Record last verified: 2021-05