NCT05030103

Brief Summary

The last decades have seen a significant increase in myopia in children and young adults. Possible cause: increased near-work (school, computer, smartphone). Rationale: Reading glasses support the accommodative effort of the eyes. By wearing reading glasses, there is less interference with the young eye´s physiological axial growth despite increased near-work. Main objective: does the use of reading glasses during near-work in children and adolescents reduce the incidence of myopia.

Trial Health

63
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for not_applicable

Timeline
68mo left

Started Oct 2023

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress32%
Oct 2023Dec 2031

First Submitted

Initial submission to the registry

August 30, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 1, 2021

Completed
2.1 years until next milestone

Study Start

First participant enrolled

October 1, 2023

Completed
8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2031

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2031

Last Updated

February 23, 2023

Status Verified

February 1, 2023

Enrollment Period

8 years

First QC Date

August 30, 2021

Last Update Submit

February 22, 2023

Conditions

Keywords

Children, prevention

Outcome Measures

Primary Outcomes (1)

  • Development of myopia

    Number of participants which develop myopia within the follow-up period of five years

    Five years

Study Arms (2)

Glasses

ACTIVE COMPARATOR

The participants are asked to wear reading glasses during near-work. The reading glasses have a lenspower of +2.0 diopters.

Device: Reading glasses, +2.0 diopters

Control

NO INTERVENTION

Age matched children and adolescents, no intervention.

Interventions

The participants in the glasses-group are asked to wear the reading glasses during near-work.

Glasses

Eligibility Criteria

Age6 Years - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Children of both sexes from the age of 6
  • Children whose parents have read and signed the declaration of consent
  • Spherical equivalent of refraction \<-0.5 dpt.
  • Distant vision in both eyes without correction 1.0
  • Willingness to wear reading glasses
  • Possibility of a five-year follow-up

You may not qualify if:

  • Children who already wear glasses
  • Astigmatism over 1.5 diopters
  • Anisometropy greater than 1.5 diopters
  • Eye diseases that affect refraction development

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Reis Augenklinik AG

Bendern, 9487, Liechtenstein

Location

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Study Officials

  • Alexander Reis, Prof. Dr.

    Reis Augenklinik AG

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Alexander Reis, Prof. Dr.

CONTACT

Amir Nassri, Dr. med.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Open, propensity score method
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 30, 2021

First Posted

September 1, 2021

Study Start

October 1, 2023

Primary Completion (Estimated)

September 30, 2031

Study Completion (Estimated)

December 31, 2031

Last Updated

February 23, 2023

Record last verified: 2023-02

Data Sharing

IPD Sharing
Will not share

Locations