NCT05015556

Brief Summary

Nondisplaced distal radial fractures are nowadays treated by plaster cast immobilization. In this study, the investigators challenge this classical standard treatment with a surgical solution: minimal invasive volar plating with pronatus quadratus sparing approach. Potential benefits of this surgical treatment are higher cost effectiveness, economical benefit, earlier recuperation of professional and recreational activities, earlier functional recuperation by faster clinical recovery (range of motion, grip strength) and decreased risk of secondary fracture displacement. Potential drawbacks are surgical risks and complications.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 3, 2021

Completed
3 months until next milestone

First Posted

Study publicly available on registry

August 20, 2021

Completed
1 year until next milestone

Study Start

First participant enrolled

September 1, 2022

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

October 5, 2022

Status Verified

October 1, 2022

Enrollment Period

1.3 years

First QC Date

June 3, 2021

Last Update Submit

October 3, 2022

Conditions

Keywords

Minimal invasiveOsteosynthesisConservative treatmentCost effectiveness

Outcome Measures

Primary Outcomes (2)

  • QALY

    Using the Short Form 36 (SF-36) assessment - cost effectiveness (The SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability.)

    1 year

  • Costs

    Direct, indirect, health insurances

    1 year

Secondary Outcomes (5)

  • Wrist ROM

    1 year

  • Grip Strength

    1 year

  • VAS

    1 year

  • DASH

    1 year

  • PRWE

    1 year

Study Arms (2)

Casting

NO INTERVENTION

Casting of the distal radius for 6 weeks

Minimal invasive volar plating

ACTIVE COMPARATOR

Muscle sparing osteosynthesis, no casting postoperatively

Procedure: Minimal invasive volar plating

Interventions

Muscle sparing osteosynthesis, no casting postoperatively

Minimal invasive volar plating

Eligibility Criteria

Age16 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Stable distal radial fractures (volar tilt \<10° dorsal tilt, \<2mm impaction, \<2mm articular depression)
  • years, professional active

You may not qualify if:

  • associated lesions, open fractures, unstable, displaced fractures
  • neurological disorder affecting the upper limb, history of wrist lesion involving the same wrist, dementia, substance abuse, severe psychiatric disorder and previous injured contralateral wrist

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of orthopaedics RZ Tienen

Tienen, 3300, Belgium

RECRUITING

MeSH Terms

Conditions

Wrist Fractures

Condition Hierarchy (Ancestors)

Wrist InjuriesArm InjuriesWounds and InjuriesFractures, Bone

Study Officials

  • Lieselot Brepoels, MD

    RZ Tienen

    STUDY DIRECTOR

Central Study Contacts

chul ki goorens, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Blinding of results by computer of the outcome results. Blinding of the patients or the care provider is not possible due to the obvious differences.
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
M.D., Principal Investigator

Study Record Dates

First Submitted

June 3, 2021

First Posted

August 20, 2021

Study Start

September 1, 2022

Primary Completion

December 31, 2023

Study Completion

December 31, 2023

Last Updated

October 5, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will not share

clinical and economical data

Locations