NCT05010083

Brief Summary

The goal of this trial is to pilot test our existing very low carbohydrate diet intervention, adapted for young adults.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
17

participants targeted

Target at below P25 for phase_1 obesity

Timeline
Completed

Started Aug 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 10, 2021

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 18, 2021

Completed
5 days until next milestone

Study Start

First participant enrolled

August 23, 2021

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2022

Completed
Last Updated

October 24, 2022

Status Verified

October 1, 2022

Enrollment Period

9 months

First QC Date

August 10, 2021

Last Update Submit

October 20, 2022

Conditions

Keywords

nutritionDiet, KetogenicDiet, Carbohydrate-Restricted

Outcome Measures

Primary Outcomes (1)

  • Change in percent bodyweight

    Measured with bodyweight scale

    4 months

Secondary Outcomes (1)

  • Change in HbA1c

    4 months

Study Arms (1)

diet and lifestyle program

EXPERIMENTAL
Behavioral: diet and lifestyle program

Interventions

See description of main arm.

diet and lifestyle program

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age 18-25
  • Obese (BMI ≥ 30)
  • Sufficient control over diet
  • Access to internet and texting
  • Living in the United States
  • Willing and able to follow intervention and complete measurements

You may not qualify if:

  • Non-English speaking
  • Pregnant, breastfeeding, or planning to be in the next 6 months
  • Vegan or vegetarian
  • Currently enrolled in weight loss program
  • Taking medications known to cause weight loss or gain
  • Taking glucose-lowering medications other than metformin
  • Type 1 diabetes
  • Cancer
  • Heart failure
  • Kidney failure
  • History of eating disorders
  • Untreated psychiatric disorder
  • History of or planned weight loss surgery
  • Consumption of greater than 30 alcoholic beverages per week

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Michigan

Ann Arbor, Michigan, 48109, United States

Location

Related Publications (1)

  • Saslow LR, O'Brien A, Raymond K, Bayandorian H, Marriott D, Moskowitz JT, Daubenmier J, Bridges D, Cousineau CM, Griauzde DH. Feasibility and acceptability of an online multicomponent very low-carbohydrate intervention in young adult women with obesity: a pilot study. Pilot Feasibility Stud. 2024 Jul 29;10(1):102. doi: 10.1186/s40814-024-01525-0.

MeSH Terms

Conditions

Obesity

Interventions

Diet

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Nutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological Phenomena

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

August 10, 2021

First Posted

August 18, 2021

Study Start

August 23, 2021

Primary Completion

June 1, 2022

Study Completion

June 1, 2022

Last Updated

October 24, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will not share

Locations