Peroneal Muscles Response to Expected and Unexpected Falls Among Young and Middle-aged Adults Before and After Neuromuscular Training

NCT05006547 | Unknown

• 1 other identifier: AU-HEA-SS-20210304:
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Proper functioning of the ankle musculature, specifically peroneal muscles, is crucial for maintaining balance and reducing the risk for falls. Evidence suggests that a decrease in aspects of neuromuscular control already starts at midlife (45-65 years). However, there is almost no information regarding the function of the ankle muscles at the middle-age as most experiments have compared young (\<35 years) and older subjects (\>65 years). Moreover, neuromuscular training can improve the function of ankle muscle in response to perturbation; yet, no previous study has compared the level of effectiveness between middle-aged and young adults.

Conditions

Healthy Participants

Outcome Measures

Primary Outcomes (8)

• Time to stabilization

  Subjects will be asked to jump from a 20 cm high box onto a force plate (i.e., expected fall).

  Within 24 hours

• Electromyography of peroneus longus- "The height of the amplitude"- expected fall

  Subjects will be asked to jump from a 20 cm high box onto a force plate (i.e., expected fall). electromyography of peroneus longus will be measured the height of the amplitude - expresses the peak of the electrical activity of the muscles.

  Within 24 hours

• Electromyography of peroneus longus- "Time to Peak"- expected fall

  Subjects will be asked to jump from a 20 cm high box onto a force plate (i.e., expected fall). electromyography of peroneus longus will be measured the "Time to Peak"- describes the time it takes for the Peroneus longus muscle to reach the peak of its electrical activity.

  Within 24 hours

• Electromyography of peroneus longus- "Time to Onset"- expected fall

  Subjects will be asked to jump from a 20 cm high box onto a force plate (i.e., expected fall). electromyography of peroneus longus will be measured the "Time to Onset" - expresses the period that passes from the beginning of the fall to the initial recruitment of the Peroneus longus.

  Within 24 hours

• Electromyography of peroneus longus- "The height of the amplitude"-unexpected fall

  Subjects will stand on a platform during a unilateral sudden 30° inversion platform perturbation that resembles an unexpected fall. electromyography of peroneus longus will be measured the "height of the amplitude" - expresses the peak of the electrical activity of the Peroneus longus muscle.

  Within 24 hours

• Electromyography of peroneus longus- "Time to Peak"-unexpected fall

  Subjects will stand on a platform during a unilateral sudden 30° inversion platform perturbation that resembles an unexpected fall. electromyography of peroneus longus will be measured the "Time to Peak"- describes the time it takes for the Peroneus longus muscle to reach the peak of its electrical activity.

  Within 24 hours

• Electromyography of peroneus longus- "Time to Onset"-unexpected fall

  Subjects will stand on a platform during a unilateral sudden 30° inversion platform perturbation that resembles an unexpected fall. electromyography of peroneus longus will be measured the "Time to Onset"- expresses the period that passes from the beginning of the fall to the initial recruitment of the Peroneus longos muscle.

  Within 24 hours

• Maximal voluntary isometric peroneal contraction force

  Subject will perform Maximal voluntary isometric peroneal contraction. The force will measured with dynamometer

  Within 24 hours

Study Arms (2)

Young adults

18\<age\<35

Other: Electromyograph Biofeedback training of the peroneal muscle

Middle aged adults

50\<age\<65

Other: Electromyograph Biofeedback training of the peroneal muscle

Interventions

Electromyograph Biofeedback training of the peroneal muscle OTHER

The exercise will be performed with the subject sitting in front of a computer monitor, on an elevated chair, and his feet will be in the air. The examiner will ask the subject to perform a maximum contraction of the paronal muscles, in an open kinematic chain. After reference, the subject will begin a five-minute practice. The practice will be divided into rounds of: eight seconds of muscle work and 15 seconds rest.

Middle aged adults; Young adults

Eligibility Criteria

• Age: 20 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy participants- Twenty-five middle-aged (50-65years) and 25 young adults (20-35 years) will be recruited.

You may qualify if:

• \- Healthy participants

You may not qualify if:

• Neurological disease accompanied by motor, sensory or cognitive impairment.
• Illness or condition that does not allow strenuous activity.
• Significant orthopedic injury to the back or lower limbs in the last six months, which limits strenuous activity or weight-bearing.
• History of orthopedic injury that includes injury to the knee or ankle ligaments.
• Taking medications that may affect stability or balance. Significant visual impairment that is not corrected using glasses/contact lenses
• Pregnancy

Sponsors & Collaborators

• Ariel University: lead

Study Sites (1)

Ariel University -The Neuromuscular & Human performance laboratory

Ariel, Israel

RECRUITING

Related Publications (1)

• Hayek R, Gottlieb U, Gutman I, Springer S. Peroneal muscle response to single-leg drop-jump and unexpected leg-drop in young and middle-aged adults before and after one session of neuromuscular training. Eur Rev Aging Phys Act. 2023 Jun 17;20(1):11. doi: 10.1186/s11556-023-00321-8.

  PMID: 37330500 DERIVED

Central Study Contacts

Shmuel Springer, Prof.

CONTACT

+972584572869; shmuels@ariel.ac.il

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 21, 2021
• First Posted: August 16, 2021
• Study Start: July 1, 2021
• Primary Completion: July 1, 2022
• Study Completion: July 1, 2022
• Last Updated: August 16, 2021

Record last verified: 2021-03

Data Sharing

• IPD Sharing: Will not share

Locations

IL (1)