Carbohydrate Antigen 19-9 in Colorectal Cancer

NCT04999072 | Unknown

• 1 other identifier: SNUH_CA19-9
• Study Type: observational
• Target: 4,972
• Locations: 1 country
• Sites: 1

Brief Summary

4,972 patients who underwent surgery for primary CRC between January 2004 and December 2015 at Seoul National University Hospital were retrospectively reviewed. CA19-9 is a valuable prognostic and diagnostic marker for CRC when used adjunctively with CEA and can be a supplementary marker with CEA to improve sensitivity, especially with elevated preoperative CA19-9.

Conditions

Colorectal Cancer

Outcome Measures

Primary Outcomes (1)

• Relapse free survival

  Recurrence and death was the event for relapse free survival

  5-year

Interventions

Colectomy for colon cancer PROCEDURE

Segmental or total colectomy was performed for colorectal cancer.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This single-centre retrospective study was based on the analysis of information from a prospectively maintained database of CRC in Seoul National University Hospital (SNUH CRC DB). Data were extracted from the SNUH CRC DB for patients who underwent surgery for primary CRC between January 2004 and December 2015 at our institution. The patients with missing data for preoperative and follow-up tumour markers were excluded from the analysis. This study was approved by the Institutional Review Board of Seoul National University Hospital (SNUH IRB; IRB no. 2007-014-1138). The approving authority waived the requirement for written informed consent owing to the retrospective study design.

You may qualify if:

• patients who underwent surgery for primary CRC between January 2004 and December 2015 at Seoul National University Hospital

You may not qualify if:

• The patients with missing data for preoperative and follow-up tumour markers

Sponsors & Collaborators

• Seoul National University Hospital: lead

Study Sites (1)

Seoul National University Hospital

Seoul, Jongnogu, 03080, South Korea

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Interventions

Colectomy

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Intervention Hierarchy (Ancestors)

Surgical Procedures, Colorectal; Digestive System Surgical Procedures; Surgical Procedures, Operative

Study Officials

• Min Jung Kim, M.D.

  Seoul National University Hospital, Republic of Korea

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: August 3, 2021
• First Posted: August 10, 2021
• Study Start: April 19, 2020
• Primary Completion: September 1, 2021
• Study Completion: December 1, 2021
• Last Updated: August 10, 2021

Record last verified: 2021-08

Locations

KR (1)